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Clean-in-Place Patents: Leaders, Trends & White Space 2026

Clean-in-Place Patents: Leaders, Trends & White Space 2026
https://www.patsnap.com/resources/blog/rd-blog/clean-in-place-and-sterilization-in-place-patent-landscape/ · Patsnap · data cut-off 2026-07-31 · downloaded from the live page
Patent Landscape · Food Machinery
Clean-in-Place and Sterilization-in-Place Patents: Who Leads and Where the Gaps Sit
  • One filer dominates. the leading assignee holds 14 of the 65 records in scope, well ahead of the field, while the ranked leaders combined (top 5) still only reach 58.5% of all records.
  • Filing has cooled from its peak. activity peaked in 2021 at 7 records and fell 71% by 2024, the last year with a complete publication picture.
  • Dispensing and cleaning dominate the claims. B67D (dispensing liquids) and B08B (cleaning) each cover roughly a third and a fifth of records respectively, while sterilizing-specific class A61L sits at just 10.8%.
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65
Published Records
58%
Top-5 Share of All Records
-71%
Filing Growth 2021→2024
US
Leading Jurisdiction

Filing growth compares 2021 (7 records) with 2024 (2) — a three-year span. 2024 is the most recent year we treat as complete: publication lags filing by roughly 18 months, so 2025 onwards are still filling in and any growth rate that ends there would understate the field. Top-5 share is the combined record count of the five largest assignees divided by all 65 records in scope (CR5), not by the ranked leaders only.

Published byPatsnap Research··7 min readSourced from Patsnap Eureka
Overview

What the Clean-in-Place and Sterilization-in-Place patent record shows

Clean-in-place (CIP) and sterilization-in-place (SIP) systems let processing equipment be cleaned or sterilized without disassembly, and the patent record here spans 65 published records filed between 2015 and 2026. The search combines core CIP/SIP terminology with technical qualifiers such as cleaning chemistry, conductivity-based endpoint detection and validation of cycles, so the set skews toward records that specify how a clean or sterile state is achieved and verified, not just that a system exists.

The receiving-office spread shows the United States as the largest single office in this set, with China, Europe and WIPO PCT filings following at meaningfully smaller volumes. That pattern points to a technology still filed primarily for domestic protection with selective international extension, rather than one pursued through broad multi-jurisdiction families.

Filing activity and technology composition, 2015-2026
  1. 1THE COCA COLA CO14
  2. 2AQUATECH INT LLC10
  3. 3H C DUKE & SON6
  4. 4GENENTECH INC5
  5. 5CLEAN SAFER SYSTEMS LLC3
  6. 6DAI NIPPON PRINTING CO LTD2
  7. 7KRAFT GENERAL FOOD CANADA2
  8. 8Shanghai Chuangjie Technology Co., Ltd.2
  9. 9DIVERSEY CORP2
  10. 10ADVANCED ELECTRON BEAMS INC2
Source: Patsnap Eureka. Assignee ranking and totals. Derived from a Patsnap search on Clean-in-Place and Sterilization-in-Place covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP

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The Numbers

Filing trend and technology composition

Two views of the same 65-record set: how filing volume has moved year over year, and how records split across the IPC subclasses that define the technical sub-areas of CIP/SIP.

Filings rose to a 2021 peak, then declined

Filings climbed to a peak of 7 records in 2021, then fell to 2 by 2024, a 71% drop over that span. Because publication lags filing by roughly 18 months, 2025 and 2026 are still filling in and should not yet be read as a continued decline.

Filings rose to a 2021 peak, then declined024681201720182019202072021202220232024202502026Most recent year is partial — publication lag means later filings are not yet visible.

Dispensing and cleaning classes carry the most claim density

B67D (dispensing liquids) appears on 33.8% of records and B08B (cleaning, general) on 29.2%, making these the most contested classes. A23G (confectionery/ice cream) and C02F (water & wastewater treatment) each sit at 20.0%, while sterilizing-specific A61L covers only 10.8% and F25C (ice making) just 4.6% — since records can carry multiple classes, these shares add to more than 100%.

Dispensing and cleaning classes carry the most claim densityB67D · Dispensing liquids2233.8%B08B · Cleaning (general)1929.2%A23G · Cocoa, confectionery & ice cre…1320.0%C02F · Water & wastewater treatment1320.0%B01D · Separation processes (filtrati…1116.9%A61L · Sterilising & disinfecting710.8%B67C · Filling & sealing containers46.2%F25C · Ice making34.6%Other2233.8%

Shares are the percentage of the 65 records in scope. A patent can carry several IPC classes, so the shares add up to more than 100%.

Source: Patsnap Eureka. Filing trend and technology composition. Derived from a Patsnap search on Clean-in-Place and Sterilization-in-Place covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.

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Key Patents

The most-cited records in this set

Representative Filing
US20210106023A12021-04-15

US20210106023A1 — Automated clean in place system for soft serve machine

H.C. DUKE & SON, LLC

A clean in place assembly for a soft serve ice cream dispenser includes an ice cream dispenser. A clean in place system having a water tank including a heater disposed therein is attached to the ice cream dispenser. A control interface is disposed on the tank and connected to operating circuitry of the ice cream dispenser. A nozzle of the dispenser is formed of a conductive metal material and includes a notch formed circumferentially about a portion of the nozzle with radiused surfaces extending to portions housing O-rings.Filed by H.C. Duke & Son, LLC, published 2021-04-15 — illustrates how equipment-specific CIP claims combine a heated water tank, control interface and nozzle geometry into a single integrated assembly.

US20210106023A1 — patent drawing 1US20210106023A1 — patent drawing 2
View full filing
Highest-citation records
#Publication no.Patent titleCitations
1US4848381AClean in place system200
2US20090014464A1Clean in Place System for Beverage Dispensers100
3US5669288ARotating drum food processor with cleaning spray accessible panels87
4CN102435224A一种过滤器在线完整性测试方法31
5EP0287194A2Clean in place system31
6US8980100B2Low energy reverse osmosis process28
7US5810059ADual channel bag filling machine with a clean in place system that cleans one channel while the other continu…21
8US20140130891A1Clean in Place System for Beverage Dispensers20
9US8678239B2Clean in place system for beverage dispensers20
10CN103693791A无菌注射用水生产工艺及无菌压缩空气制备方法18

Ranked by citation count within the searched corpus; older filings accumulate more citations by nature, so treat this as a signal of influence rather than current importance.

Patent titles are shown in the language they were filed in, not translated, so that each record stays verifiable against the original filing — a translated title will not match in Eureka or in any national register. Each row carries its publication number; clicking a row searches Eureka by that number.

Source: Patsnap Eureka. Citation counts and representative records. Derived from a Patsnap search on Clean-in-Place and Sterilization-in-Place covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
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Insights

What the data means for filing strategy

Three read-outs from the concentration, trend and classification data that matter for anyone deciding where to file next.

Concentration
58.5% top 5
of 65 records

One leader, then a fast drop-off

The leading assignee holds 14 records — nearly a quarter of the field on its own — while the top 5 combined reach 58.5% of all 65 records. The gap between the leader and fifth place (3 records) is wide, meaning most other filers hold only a handful of records each.

Ranked leaders, 24 companies
Momentum
-71%
2021 to 2024

Peak filing has passed, for now

Filings peaked at 7 in 2021 and fell to 2 by 2024, a 71% decline over that span. Given the 18-month publication lag, 2025-2026 figures are not yet complete enough to call a continued slowdown.

2021 peak year: 7 records
Technology mix
33.8%
of records in B67D

Dispensing equipment carries the claim load

B67D (dispensing liquids) and B08B (cleaning) are the two most heavily claimed subclasses, together suggesting most CIP innovation is being captured at the equipment-and-cleaning-cycle level rather than as standalone sterilization chemistry.

A61L (sterilizing): 10.8% of records
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Co-filing is rare in this set
AssigneeCo-assigneeShared families
Aquatech International LLCAQUATECH INTERNATIQNAL LLC1

The strongest co-assignee pair identified appears only once, indicating CIP/SIP patenting here is overwhelmingly done by single assignees rather than joint ventures or research partnerships.

Source: Patsnap Eureka. Co-assignee relationships and derived observations. Derived from a Patsnap search on Clean-in-Place and Sterilization-in-Place covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
Players

Who holds the ground, and what is still open

The ranked leaders make up a field of 24 companies, dominated by one filer with a long tail of single- and few-record entrants behind it.

Leader
14 records
of 65 in scope

A clear volume leader

The top-ranked assignee holds 14 of the 65 records in scope, more than four times the fifth-place holder's 3 records. That gap suggests a sustained, deliberate filing programme rather than opportunistic patenting.

Leader: 14 of 65 records
Mid-field
3 records
fifth place

A thin second tier

Fifth place holds just 3 records, and tenth place only 2 — the field thins out quickly past the leader, leaving room for a determined new entrant to build a meaningful position with a handful of well-targeted filings.

Tenth place: 2 records
Momentum
0 in latest year
across tracked assignees

Little recent activity from named leaders

None of the assignees tracked for recent-year momentum show filings in the latest year, consistent with the broader post-2021 decline and the publication lag affecting the newest data.

Momentum tracked across 6 assignees
🔍
Under-claimed sub-areas worth a closer look
Branches where filing density is comparatively thin relative to the core dispensing and cleaning classes.
Conductivity-based endpoint detectionRiboflavin coverage validation methodsDead-leg design minimisationEnergy-usage optimised CIP cyclesIce-making equipment sterilization (F25C)
Rank all filers by momentum →
Recent-year filing momentum by assignee
AssigneeRecent yearYoY
The Coca-Cola Company0
Aquatech International LLC0
H C DUKE & SON0
Genentech, Inc.0
DIVERSEY CORP0
Jiangsu Dahongying Hengshun Pharmaceutical Co., Ltd.0
Dai Nippon Printing Co., Ltd.0
Advanced Electron Beams, Inc.0
Source: Patsnap Eureka. Assignee-level momentum. Derived from a Patsnap search on Clean-in-Place and Sterilization-in-Place covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
What's Next

Where to take this analysis

The dataset points to a concentrated leader, a cooling filing trend, and technology claims clustered on dispensing and cleaning rather than sterilization chemistry itself.

Map claim boundaries around the leader's portfolio

With one assignee holding 14 of 65 records, understanding exactly what their claims cover — and where the boundaries end — is the first step before filing adjacent art.

Explore claim scope in Eureka

Watch the under-claimed validation and endpoint methods

Conductivity-based endpoint detection and cycle validation appear as qualifiers in the search but are thinly represented as dedicated claims, suggesting room to file there.

Run a white-space search in Eureka

Track whether 2025-2026 filings reverse the decline

Because publication lags filing by about 18 months, the true trajectory of the post-2021 slowdown will not be clear until later filings surface.

Set up filing alerts in Eureka
Source: Patsnap Eureka. Forward-looking reading of the same dataset. Derived from a Patsnap search on Clean-in-Place and Sterilization-in-Place covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
FAQ

Common questions about Clean-in-Place and Sterilization-in-Place patents

Answers are grounded in the same dataset. Derived from a Patsnap search on Clean-in-Place and Sterilization-in-Place covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP

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Disclaimer. This page is generated from Patsnap Eureka data drawn from a limited snapshot of global patent and scientific-literature records, and is provided for general information and reference only.

Patent data carries inherent limitations: recent filings (typically the most recent 18–24 months) are under-counted due to standard publication lag; counts may be reported at either a patent-family or a patent-record basis and are not always directly comparable; classification, applicant-name, and citation data may contain errors, duplicates, or omissions; and the underlying search query defines and constrains the scope shown. As a result, the analysis may be incomplete or inaccurate and may not reflect the full technology landscape.

Nothing on this page constitutes an exhaustive prior-art, novelty, freedom-to-operate, or validity search, nor does it constitute legal, financial, investment, or professional advice, and it should not be relied upon as such. Any patent, commercial, or strategic decision should be verified independently and reviewed with qualified patent, legal, and domain professionals. Patsnap makes no warranties, express or implied, as to the accuracy, completeness, or fitness for any particular purpose of the information presented.

Machine translation. Assignee and organisation names originally recorded in Chinese, Japanese or Korean have been rendered into English by an AI translation step so that the tables stay readable. These renderings are best-effort and may not match a company’s registered English name; the original name is what the underlying patent record carries, and it is what any Eureka query launched from this page uses.

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