https://www.patsnap.com/resources/blog/rd-blog/hair-repair-and-bond-building-patent-landscape/ · Patsnap · data cut-off 2026-07-31 · downloaded from the live page
Patent Landscape · Hair Care
Hair Repair and Bond Building Patents: Who Leads and Where the Filing Has Gone Quiet
  • A single filer dominates the ranking. the leading assignee holds 557 records against 111 at fifth place and 32 at tenth, a steep drop-off rather than a gradual one.
  • Filing has cooled from its 2017 peak. 107 records that year against 85 in 2021 and 34 in 2024, a -60% move over that three-year span (2025-26 figures are still filling in under publication lag).
  • Cosmetic and biotech claims overlap heavily. A61K medicinal preparations covers 59.1% of the 1,406 records in scope and C12N genetic-engineering claims cover 41.7%, alongside A61Q cosmetics use at 42.7% — three large, overlapping claim zones rather than one clean category.
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1,406
Published Records
-60%
Filing Growth 2021→2024
US
Leading Jurisdiction
100
Active Filers Ranked

Filing growth compares 2021 (85 records) with 2024 (34) — a three-year span. 2024 is the most recent year we treat as complete: publication lags filing by roughly 18 months, so 2025 onwards are still filling in and any growth rate that ends there would understate the field.

Published byPatsnap Research··7 min readSourced from Patsnap Eureka
Overview

What this landscape covers

This review covers 1,406 published records filed or published between 2015 and mid-2026 that combine hair-repair or bond-building treatment claims with mechanisms such as disulfide bond chemistry, tensile recovery, cuticle smoothing, protein loss reduction, treatment durability or claim-support testing. The scope spans both formulation-side cosmetic filings and the genetic-engineering and protein-science filings that underpin some of the underlying repair chemistry, which is why medicinal preparations and microorganism/genetic-engineering classes both appear at high volume alongside straightforward cosmetics-use claims.

Filings peaked in 2017 and have since declined through the last complete year in this dataset, 2024. Because publication typically lags filing by around 18 months, the 2025 and 2026 counts shown in the trend are still incomplete and should not be read as a continued fall.

Filing activity, 2017-2026
  1. 1THE BROAD INST INC557
  2. 2MASSACHUSETTS INST OF TECH549
  3. 3PRESIDENT & FELLOWS OF HARVARD COLLEGE206
  4. 4LOREAL SA125
  5. 5UNILEVER NV111
  6. 6OLAPLEX INC76
  7. 7UNILEVER PLC70
  8. 8HINDUSTAN UNILEVER LTD38
  9. 9LIVING PROOF INC32
  10. 10K18 INC32
Source: Patsnap Eureka. Assignee ranking and totals. Derived from a Patsnap search on Hair Repair and Bond Building covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP

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The Numbers

Filing trend and technology composition

Two views of the same 1,406-record set: how filing volume has moved year over year, and which IPC subclasses carry the claims.

From a 2017 peak to a cooling filing pace

Annual filings ran from 107 records in 2017 down to 5 in the most recent (partial) year. The reliable comparison is 2021 to 2024: 85 records down to 34, a -60% change over three years. Treat 2025 and 2026 as undercounted rather than as evidence the field has stopped.

From a 2017 peak to a cooling filing pace030609012010720172018201920202021202220232024202552026Most recent year is partial — publication lag means later filings are not yet visible.

Cosmetic and biotech claims sit on top of each other

A61K (medicinal preparations) appears in 59.1% of the 1,406 records, A61Q (cosmetics use) in 42.7%, and C12N (microorganisms and genetic engineering) in 41.7%. Because records can carry multiple IPC codes, these figures overlap rather than sum to 100%; smaller subclasses such as C07K (peptides and proteins, 6.7%) and A45D (hairdressing equipment, 5.3%) mark narrower, more specific claim territory.

Cosmetic and biotech claims sit on top of each otherA61K · Medicinal preparations83159.1%A61Q · Cosmetics use60142.7%C12N · Microorganisms & genetic engin…58641.7%C07K · Peptides & proteins946.7%A45D · Hairdressing & toilet equipment755.3%A61P · Therapeutic activity of compou…594.2%C12Q · Measuring & testing involving …433.1%A01K · Animal husbandry & fishing392.8%Other49835.4%

Shares are the percentage of the 1,406 records in scope. A patent can carry several IPC classes, so the shares add up to more than 100%.

Source: Patsnap Eureka. Filing trend and technology composition. Derived from a Patsnap search on Hair Repair and Bond Building covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.

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Key Patents

Representative and most-cited filings

Representative Filing
US20040258652A12004-12-23

Hair treatment compositions and hair after-treatment compositions for protection against damage by chemical treatment and for the repair of already damaged hair comprising as active substances alkylguanidine compounds (US20040258652A1)

GOLDSCHMIDT GMBH

Hair treatment compositions and hair after-treatment compositions are provided for the prevention of damage by chemical treatment compositions and for the repair of already damaged hair, wherein, as active substances, at least one of the compounds of the general formulae (I) and/or (II) are additionally used.Filed by Goldschmidt GmbH, published 2004-12-23 — predates the bulk of this dataset and illustrates how early alkylguanidine-based repair chemistry was claimed before disulfide-bond and tensile-recovery language became standard.

US20040258652A1 — patent drawing 1US20040258652A1 — patent drawing 2
View full filing
Most-cited records in this dataset
#Publication no.Patent titleCitations
1WO2014093622A2Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and the…1,491
2US20140179770A1Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and the…981
3US20160208243A1Novel crispr enzymes and systems863
4US9790490B2CRISPR enzymes and systems756
5US20140242699A1Delivery, engineering and optimization of systems, methods and compositions for sequence manipulation and the…727
6WO2014204728A1Delivery, engineering and optimization of systems, methods and compositions for targeting and modeling diseas…602
7WO2014204729A1Delivery, use and therapeutic applications of the crispr-CAS systems and compositions for targeting disorders…555
8WO2015089419A2Delivery, use and therapeutic applications of the crispr-CAS systems and compositions for targeting disorders…517
9US6992172B1Recombinant gelatins424
10WO2015089462A1Delivery, use and therapeutic applications of the crispr-CAS systems and compositions for genome editing352

Citation counts favour older filings in any searched corpus; read them as a signal of influence on later filings, not as a ranking of current commercial relevance.

Each row carries its publication number; clicking a row searches Eureka by that number.

Source: Patsnap Eureka. Citation counts and representative records. Derived from a Patsnap search on Hair Repair and Bond Building covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
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Insights

What the data tells a filing strategy

Three observations shape where new filings are likely to clear prior art and where they will collide with dense, established claim territory.

Concentration
557 vs 111 vs 32
leader / 5th / 10th place

One filer, then a steep drop

The leading assignee's record count is roughly five times the fifth-placed filer's and over seventeen times the tenth-placed filer's. That gap is a cliff, not a gradient — the ranked leaders below the top spot are comparatively close to each other.

From the 100-company assignee ranking
Momentum
-60%
2021 → 2024 filings

Volume down from its 2017 high

Filings dropped from 85 in 2021 to 34 in 2024. Several of the largest historical filers show -90% to -100% year-on-year moves in the latest recorded year, though that latest year is still incomplete under publication lag.

2021-2024 is the reliable comparison window
Composition
59.1% / 42.7% / 41.7%
share of 1,406 records

Three overlapping claim zones

Medicinal-preparation, cosmetics-use and genetic-engineering classes each cover well over a third of records, meaning most filings sit at an intersection rather than in one clean bucket. Narrower classes like peptides/proteins (6.7%) and hairdressing equipment (5.3%) are comparatively open.

IPC subclass shares, 1,406-record base
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Eureka can read the same corpus for gaps instead of for coverage: under-claimed branches adjacent to hair repair and bond building, with the prior art for and against each one.

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Co-filing concentrates among a small research cluster
AssigneeCo-assigneeShared families
Broad Institute, Inc.Massachusetts Institute of Technology550
Broad Institute, Inc.President and Fellows of Harvard College205
Massachusetts Institute of TechnologyPresident and Fellows of Harvard College204
Unilever N.V.Unilever PLC54
Broad Institute, Inc.ZHANG FENG42
Massachusetts Institute of TechnologyZHANG FENG42
Unilever N.V.Hindustan Unilever Limited23
Unilever PLCHindustan Unilever Limited23

The strongest co-assignee pairings in this dataset link the same handful of research institutions repeatedly (550 and 205+ shared records between top pairs), rather than spreading across many bilateral partnerships — a sign that the deepest genetic-engineering IP here sits inside one collaborating cluster.

Source: Patsnap Eureka. Co-assignee relationships and derived observations. Derived from a Patsnap search on Hair Repair and Bond Building covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
Players

Who holds the ground, and where it thins out

The ranking runs 100 companies deep and is heavily front-loaded: research institutions dominate the top of the table on record count, while formulation and consumer-brand filers sit further down with smaller, steadier portfolios.

Leader
557 records
top of the 100-company ranking

A research-institution cluster leads by volume

The top of the ranking is held by academic and research-institute filers whose portfolios span genetic-engineering methods applicable well beyond hair care, which is part of why C12N appears so heavily in the IPC mix.

Assignee ranking, 1,406-record base
Consumer brands
Mid-table presence
formulation-side filers

Cosmetics majors file steadily, not aggressively

Established personal-care companies appear through the ranking with formulation and bond-repair treatment claims, but none approach the record counts of the leading research-institution filers.

Cross-referenced against A61Q and A45D classes
Momentum
-90% to -100% YoY
latest recorded year, largest filers

Even the largest filers have slowed on paper

Several of the historically largest assignees show sharp year-on-year drops in the latest recorded year. Given the roughly 18-month publication lag, this reads as incomplete data rather than a confirmed stop in filing.

Recent-year momentum by assignee
🔍
Under-claimed branches worth checking before filing
Smaller IPC shares point to narrower, less crowded claim space within the same search scope.
Cuticle-smoothing surface treatments (A45D)Peptide-based bond repair (C07K)Enzyme-assay claim support methods (C12Q)Therapeutic-activity formulation claims (A61P)Animal-hair/husbandry applications (A01K)
Rank all filers by momentum →
Filing momentum by assignee
AssigneeRecent yearYoY
Broad Institute, Inc.2-90%
Massachusetts Institute of Technology2-90%
President and Fellows of Harvard College0-100%
L'Oréal SA0-100%
Unilever N.V.0
Olaplex, Inc.0-100%
Unilever PLC0
Hindustan Unilever Limited0
Source: Patsnap Eureka. Assignee-level momentum. Derived from a Patsnap search on Hair Repair and Bond Building covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
What's Next

Where to take this

The dataset points to next steps depending on whether the goal is freedom-to-operate, portfolio benchmarking or spotting where to file.

Map claims against the leading portfolios

With one filer holding 557 of the ranked records, a freedom-to-operate check should start there before looking at the long tail.

Explore assignee portfolios in Eureka

Stress-test an under-claimed branch

Peptide-based repair and cuticle-smoothing equipment claims sit at single-digit shares of the record base — worth a closer prior-art pull before drafting.

Run a white-space search in Eureka

Track the 2025-2026 filings as they land

Because publication lags filing by about 18 months, the real 2025 picture will only become visible over the next year or so.

Set up filing alerts in Eureka
Source: Patsnap Eureka. Forward-looking reading of the same dataset. Derived from a Patsnap search on Hair Repair and Bond Building covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
FAQ

Common questions about this landscape

Answers are grounded in the same dataset. Derived from a Patsnap search on Hair Repair and Bond Building covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP

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Disclaimer. This page is generated from Patsnap Eureka data drawn from a limited snapshot of global patent and scientific-literature records, and is provided for general information and reference only.

Patent data carries inherent limitations: recent filings (typically the most recent 18–24 months) are under-counted due to standard publication lag; counts may be reported at either a patent-family or a patent-record basis and are not always directly comparable; classification, applicant-name, and citation data may contain errors, duplicates, or omissions; and the underlying search query defines and constrains the scope shown. As a result, the analysis may be incomplete or inaccurate and may not reflect the full technology landscape.

Nothing on this page constitutes an exhaustive prior-art, novelty, freedom-to-operate, or validity search, nor does it constitute legal, financial, investment, or professional advice, and it should not be relied upon as such. Any patent, commercial, or strategic decision should be verified independently and reviewed with qualified patent, legal, and domain professionals. Patsnap makes no warranties, express or implied, as to the accuracy, completeness, or fitness for any particular purpose of the information presented.

Machine translation. Assignee and organisation names originally recorded in Chinese, Japanese or Korean have been rendered into English by an AI translation step so that the tables stay readable. These renderings are best-effort and may not match a company's registered English name; the original name is what the underlying patent record carries, and it is what any Eureka query launched from this page uses.