https://www.patsnap.com/resources/blog/rd-blog/human-milk-oligosaccharide-production-patent-landscape/ · Patsnap · data cut-off 2026-07-31 · downloaded from the live page
Patent Landscape · Nutrition Products
Human Milk Oligosaccharide Production Patents: Concentration and White Space
  • One assignee holds every record in scope. all 38 published records in scope trace to a single company, leaving no rival cluster to benchmark against.
  • Filing peaked in 2017 and has not returned. 32 records published that year against a filing trend that falls to zero by 2026, with 2021-to-2024 activity down 100% on the evidence available.
  • Microorganism engineering dominates the claim space. C12N covers 97.4% of the 38 records, while fermentation-specific C12P claims sit far behind at 21.1%, a gap worth checking before drafting.
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38
Published Records
-100%
Filing Growth 2021→2024
US
Leading Jurisdiction
2017
Peak Filing Year

Filing growth compares 2021 (2 records) with 2024 (0) — a three-year span. 2024 is the most recent year we treat as complete: publication lags filing by roughly 18 months, so 2025 onwards are still filling in and any growth rate that ends there would understate the field.

Published byPatsnap Research··6 min readSourced from Patsnap Eureka
Overview

What the filing record shows

Patent activity around human milk oligosaccharide production in this dataset is unusually narrow: 38 published records, all of them attributable to a single assignee. That is not typical of a competitive field with entrants jockeying for position — it reads more like one company's sustained programme around engineered microbial strains and the enzymes used to build or clean up oligosaccharide structures, with everyone else absent from the public record captured here.

The technology composition backs this up. Claims cluster overwhelmingly around microorganism and genetic-engineering work (C12N), with a secondary presence in animal-feed applications (A23K) and a smaller footprint in fermentation and enzymatic synthesis (C12P). Purification, structural-identity confirmation and food-approval-adjacent claims are comparatively thin, which is where a newcomer's freedom to operate is least contested.

Filing activity and technology mix, 2015-2026
  1. 1Novozymes A/S38
Source: Patsnap Eureka. Assignee ranking and totals. Derived from a Patsnap search on Human Milk Oligosaccharide Production covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
The Data

Filing trend and technology composition

Two views of the same 38 records: when they were published, and which IPC subclasses they carry. Because a record can carry more than one class, the class shares add up to more than 100% of the record total.

Filing trend, 2015-2026

Publications peak sharply at 32 in 2017 and taper toward zero by 2026. The most recent years are understated because publication typically lags filing by roughly 18 months, so 2025 and 2026 should not be read as a real drop-off yet — but 2021-to-2024 is complete enough to show an -100% change, and that figure is real.

Filing trend, 2015-20260102030403220172018201920202021202220232024202502026Most recent year is partial — publication lag means later filings are not yet visible.

Technology composition by IPC subclass

C12N (microorganisms and genetic engineering) touches 97.4% of the 38 records, making it the dominant claim territory. A23K (animal feed) sits at 57.9%, C12P (fermentation and enzymatic synthesis) at 21.1%, A61K (medicinal preparations) at 5.3% and C07K (peptides and proteins) at 2.6% — the last three are where claim density thins out.

Technology composition by IPC subclassC12N · Microorganisms & genetic engin…3797.4%A23K · Animal feed2257.9%C12P · Fermentation & enzymatic synth…821.1%A61K · Medicinal preparations25.3%C07K · Peptides & proteins12.6%

Shares are the percentage of the 38 records in scope. A patent can carry several IPC classes, so the shares add up to more than 100%.

Source: Patsnap Eureka. Filing trend and technology composition. Derived from a Patsnap search on Human Milk Oligosaccharide Production covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.

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Key Patents

The most-cited records in this dataset

Representative Filing
US20190127717A12019-05-02

Compositions Comprising Polypeptides having Galactanase Activity and Polypeptides having Beta-Galactosidase Activity

NOVOZYMES A/S

The present invention relates to compositions comprising polypeptides having galactanase activity and polypeptides having beta-galactosidase activity for use in e.g. animal feed. The present invention further relates to polypeptides having beta-galactosidase activity, polypeptides having galactanase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.Filed by Novozymes, published 2019-05-02, this filing sits at the centre of the enzyme-composition cluster that anchors the dataset's most-cited records.

View filing details
Most-cited records
#Publication no.Patent titleCitations
1US20190289880A1Polypeptides having Alpha-Galactosidase Activity and Polynucleotides Encoding Same6
2WO2017202997A1Compositions comprising polypeptides having galactanase activity and polypeptides having beta-galactosidase a…6
3WO2017202979A1Polypeptides having alpha-galactosidase activity and polynucleotides encoding same4
4WO2017202966A1Polypeptides having alpha-galactosidase activity and polynucleotides encoding same4
5WO2017202946A1Compositions comprising polypeptides having galactanase activity and polypeptides having beta-galactosidase a…3
6US11058129B2Animal feed additives2
7US20190144902A1Polypeptides Having Alpha-Galactosidase Activity and Polynucleotides Encoding Same2

Citation counts reward older records simply because they have had more time to be cited; read them as a signal of influence within this corpus, not as a measure of current importance.

Publication numbers are shown where the record carries one (7 of 7 rows); clicking a row searches Eureka by that number.

Source: Patsnap Eureka. Citation counts and representative records. Derived from a Patsnap search on Human Milk Oligosaccharide Production covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
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Insights

What the numbers mean for a filing decision

Read together, the trend, the concentration figures and the IPC mix point to a field with one incumbent and several under-claimed branches rather than an open contest between many players.

Concentration
100.0%
of 38 records

One assignee, the whole record

The top 5 combined figure and the top 1 combined figure are identical: 38 of 38 records, 100.0% of all records in scope. There is no second cluster to compare against in this dataset.

Source: assignee ranking, this dataset
Filing momentum
-100%
2021 to 2024

Growth has not reappeared since the 2017 peak

The peak year was 2017 at 32 records; by 2024, the last year treatable as complete, filing had fallen to zero from 2021's count of 2 — a -100% change over that span.

Publication lag means 2025-2026 figures will still fill in
Claim density
97.4%
carry C12N

Microorganism engineering is the crowded territory

C12N touches 37 of the 38 records. A23K (animal feed) is the next largest at 57.9%, while C12P (fermentation and enzymatic synthesis) trails at 21.1% — a gap that matters for anyone drafting fermentation-process claims.

Source: IPC subclass distribution, this dataset
Eureka AI Agent
Looking for what nobody has claimed yet?

Eureka can read the same corpus for gaps instead of for coverage: under-claimed branches adjacent to human milk oligosaccharide production, with the prior art for and against each one.

Find the white space →
Source: Patsnap Eureka. Co-assignee relationships and derived observations. Derived from a Patsnap search on Human Milk Oligosaccharide Production covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
Players

Who is actually filing

The ranked list this dataset returns names a single assignee across all 38 records, with recent-year momentum for that assignee at zero in the latest year captured.

Incumbent
38
records

The sole ranked assignee

Every record in this dataset's assignee ranking belongs to one company, whose portfolio centres on engineered enzymes and host strains used in oligosaccharide-adjacent fermentation and animal-feed applications.

Recent-year momentum: 0 in the latest year
Filing geography
12
US filings

United States leads receiving offices

The United States receives the most filings at 12, ahead of the European Patent Office at 8, WIPO's PCT route at 4, and Australia and Brazil at 3 each.

Source: receiving office counts, this dataset
Structural gap
2.6%
carry C07K

Peptide and protein claims are thin

Only 1 of the 38 records carries a C07K peptide/protein classification, and A61K medicinal-preparation claims cover just 2 records — both far behind the C12N and A23K clusters.

Source: IPC subclass distribution, this dataset
🔍
Under-claimed branches worth checking before you draft
These sit outside the dense C12N/A23K core and carry noticeably fewer records in this dataset.
Byproduct removal from fermentation brothStructural identity confirmation methodsSpray-dried powder formulationNovel food approval documentationPurification chromatography for HMOs
Rank all filers by momentum →
Recent-year filing momentum
AssigneeRecent yearYoY
Novozymes A/S0
Source: Patsnap Eureka. Assignee-level momentum. Derived from a Patsnap search on Human Milk Oligosaccharide Production covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
What's Next

Where to take this

The concentration and white-space patterns above are a starting point, not a full clearance opinion. The next steps depend on whether you are drafting, licensing or scouting for acquisition targets.

Model a specific claim against the incumbent's portfolio

Run a candidate claim in purification chromatography or byproduct removal against the full text of the incumbent's filings to see how much room actually remains.

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Track the next publication window

Because publication lags filing by roughly 18 months, the 2025-2026 figures will keep moving; set a watch on new C12P and A61K filings before committing to a filing strategy.

Set up monitoring in Patsnap Eureka
Source: Patsnap Eureka. Forward-looking reading of the same dataset. Derived from a Patsnap search on Human Milk Oligosaccharide Production covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
FAQ

Common questions on this landscape

Answers are grounded in the same dataset. Derived from a Patsnap search on Human Milk Oligosaccharide Production covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP

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Disclaimer. This page is generated from Patsnap Eureka data drawn from a limited snapshot of global patent and scientific-literature records, and is provided for general information and reference only.

Patent data carries inherent limitations: recent filings (typically the most recent 18–24 months) are under-counted due to standard publication lag; counts may be reported at either a patent-family or a patent-record basis and are not always directly comparable; classification, applicant-name, and citation data may contain errors, duplicates, or omissions; and the underlying search query defines and constrains the scope shown. As a result, the analysis may be incomplete or inaccurate and may not reflect the full technology landscape.

Nothing on this page constitutes an exhaustive prior-art, novelty, freedom-to-operate, or validity search, nor does it constitute legal, financial, investment, or professional advice, and it should not be relied upon as such. Any patent, commercial, or strategic decision should be verified independently and reviewed with qualified patent, legal, and domain professionals. Patsnap makes no warranties, express or implied, as to the accuracy, completeness, or fitness for any particular purpose of the information presented.

Machine translation. Assignee and organisation names originally recorded in Chinese, Japanese or Korean have been rendered into English by an AI translation step so that the tables stay readable. These renderings are best-effort and may not match a company's registered English name; the original name is what the underlying patent record carries, and it is what any Eureka query launched from this page uses.