Hydrolyzed Formula Patents: Top Companies & Filing Trends 2026
- 79.7% concentration. The top five assignees account for 173 of 217 records in scope, leaving a thin tail behind them.
- Peak filing year already behind us. Activity crested in 2019 at 33 records, with the most recent years still filling in behind the publication lag.
- Protein chemistry dominates the claim map. A23J peptide and protein classes touch 56.2% of records, well ahead of the dairy-specific A23C class at 24.0%.
Top-5 share is the combined record count of the five largest assignees divided by all 217 records in scope (CR5), not by the ranked leaders only.
What the hydrolyzed and hypoallergenic formula patent record shows
Hydrolyzed and hypoallergenic infant formula sits at the intersection of protein chemistry and clinical nutrition: enzymatic hydrolysis breaks intact milk proteins into smaller peptides to reduce residual allergenicity, while formulators separately fight the bitterness those same peptides introduce. The patent record in scope, 217 published records from 2015 through the middle of 2026, tracks claims across peptide weight control, enzyme selection, taste-masking, and the clinical tolerance data used to support labelling claims.
Filing concentrates hard at the top of the assignee ranking, and the technology composition shows protein and peptide chemistry (A23J, C07K) sitting alongside medicinal-preparation claims (A61K, A61P) more often than dairy-specific processing (A23C) alone, which points to a field increasingly argued on biochemical and clinical grounds rather than pure food processing.
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Filing trend and technology composition
Two views of the same 217-record dataset: filing activity by year, and where those records sit across IPC subclasses. Because a single record can carry several IPC codes, the class shares below add up to well over 100% of the record total.
Filing trend, 2015–2026
Filings peaked in 2019 at 33 records. Recent years understate true activity because publication typically lags filing by around 18 months, so 2025-2026 figures will keep rising as later-filed applications publish.
Technology composition by IPC subclass
A23L (foods and non-alcoholic beverages) touches 75.1% of the 217 records, and A23J (proteins and food peptides) touches 56.2%. Medicinal-preparation claims under A61K appear in 47.0% of records, showing how often formula claims are framed with a therapeutic rather than purely nutritional angle.
Shares are the percentage of the 217 records in scope. A patent can carry several IPC classes, so the shares add up to more than 100%.
Go deeper on Hydrolyzed and Hypoallergenic Formulas with Eureka
This page is one run against one query. Ask Eureka your own question about hydrolyzed and hypoallergenic formulas and every answer comes back with the patent numbers behind it.
Try EurekaThe most-cited records in this field
Method for decreasing bitterness and improving taste of protein-free and hydrolyzed infant formulas
The present invention relates to a method for decreasing the bitterness or improving the taste of a protein-free or hydrolyzed infant formula. The method comprises intermixing ingredients of the formula and adjusting the pH of the formula to between about 6.5 and about 7.2.Filed by Mead Johnson Nutrition Company, this record targets one of the field's persistent formulation problems: hydrolysis reduces allergenicity but generates bitter peptides, and pH adjustment during mixing is claimed as a fix.
View full filing in Eureka| # | Publication no. | Patent title | Citations |
|---|---|---|---|
| 1 | WO2002045524A2 | Prolyl endoprotease from aspergillus niger | 138 |
| 2 | WO2000042863A1 | A hypoallergenic composition containing tolerogenic peptides inducing oral tolerance | 84 |
| 3 | US20040241664A1 | Protein Hydrolysates Enriched In Peptides Having A Carboxy Terminal Proline Residue | 79 |
| 4 | WO2002045523A2 | Protein hydrolysates enriched in peptides having a carboxy terminal proline residue | 64 |
| 5 | US20020037357A1 | Hypoallergenic composition containing tolerogenic peptides | 36 |
| 6 | US20040241791A1 | Protein hydrolysates enriched in peptides having a carboxy terminal proline residue | 29 |
| 7 | WO2012042013A1 | Milk-based protein hydrolysates and infant formulae and nutritional compositions made thereof | 27 |
| 8 | WO2015090347A1 | Newly identified peptides for use in the induction of oral tolerance in young mammals | 22 |
| 9 | US6737076B2 | Hypoallergenic composition containing tolerogenic peptides | 18 |
| 10 | US7309595B2 | Protein hydrolysates enriched in peptides having a carboxy terminal proline residue | 17 |
Citation counts inside a searched corpus favour older filings that have had more time to accumulate citations; treat them as a signal of influence on the field, not of current commercial relevance.
Each row carries its publication number; clicking a row searches Eureka by that number.
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Browse MCP servers →What the numbers mean for a filing decision
The dataset points to a field where a small group of assignees has already built dense claim coverage around core hydrolysis and taste-masking methods, while clinical-tolerance and labelling-support claims remain comparatively open.
Five assignees hold most of the field
The leading assignee alone accounts for 78 records, and the top five combined reach 173 of the 217 records in scope. That leaves a long tail of single- or few-filing entrants competing for the remaining space.
Peptide chemistry outweighs dairy processing
A23J protein and peptide claims appear in more records than A23C dairy-specific processing (24.0%), suggesting the active argument in recent filings is about peptide weight and enzyme selection rather than raw milk processing.
Activity has already crested once
2019 remains the peak filing year so far, at 33 records. Because publication lags filing by roughly 18 months, the apparent decline into 2025-2026 is partly an artefact of that lag rather than a real drop in activity.
Eureka can read the same corpus for gaps instead of for coverage: under-claimed branches adjacent to hydrolyzed and hypoallergenic formulas, with the prior art for and against each one.
| Assignee | Co-assignee | Shared families |
|---|---|---|
| Societe des Produits Nestle SA | Nestec SA | 6 |
| DSM IP Assets B.V. | EDENS LUPPO | 4 |
| MAYNARD FRANCOISE | PANCHAUD ALEXANDRE | 3 |
| MAYNARD FRANCOISE | MERCENIER ANNICK | 3 |
| MAYNARD FRANCOISE | BUREAU FRANZ ISABELLE | 3 |
| MAYNARD FRANCOISE | AFFOLTER MICHAEL | 3 |
| DSM IP Assets B.V. | VAN DER HOEVEN ROBERTUS ANTONIUS MIJNDERT | 2 |
| DSM IP Assets B.V. | HOEVEN VAN DER ROBERTUS ANTONIUS MIJNDERT | 2 |
Ten co-assignee pairs appear in the dataset, with the strongest pairing linked to a single corporate group filing jointly across related entities, and a second pairing linking an ingredients specialist to a smaller named co-filer.
Who is filing, and where the field is still open
The ranked list covers 32 companies, the full set the data endpoint returns for this search, not a top-50 or top-100 cut. Momentum in the latest complete year is flat to zero across the leading names, consistent with the publication-lag effect rather than a slowdown in real filing activity.
A single assignee anchors the field
The leading assignee's 78 records is more than four times the fifth-place count of 17, and its filings run across bitterness reduction, enzyme selection and hypoallergenic formulation together rather than any single narrow claim area.
A mid-tier cluster with real but smaller footprints
Fifth place sits at 17 records, still well ahead of the tenth-place count of 3, showing a fairly steep drop-off rather than a gradual taper across the ranked assignees.
Almost the whole field sits in ten hands
The top 10 combined account for 213 of the 217 records in scope, 98.2% of the total. Anyone outside that group is filing into a field where the dominant claim territory is already staked out by a small number of firms.
| Assignee | Recent year | YoY |
|---|---|---|
| Societe des Produits Nestle SA | 0 | — |
| DSM IP Assets B.V. | 0 | — |
| Nestec SA | 0 | — |
| Mead Johnson Nutrition Company | 0 | — |
| N.V. Nutricia | 0 | — |
| MJN US Holdings LLC | 0 | — |
| Milk Care Co Inc | 0 | — |
| MAYNARD FRANCOISE | 0 | — |
Where to take this next
The figures above describe where the field has been. Deciding where to file next means running the same questions against the live, unfiltered dataset.
Check freedom to operate against the leader's full claim set
With one assignee holding 78 of 217 records, a focused freedom-to-operate review of that portfolio alone will clear or flag most of the field's core hydrolysis and taste-masking claims.
Run an FTO check in EurekaTrack the under-claimed branches before they fill in
Clinical-tolerance and labelling-support claims show thinner coverage than core hydrolysis methods; monitoring new filings there early gives more room to stake out defensible claim language.
Set up monitoring in EurekaRe-run the trend once later years finish publishing
Because publication lags filing by around 18 months, 2025-2026 filing counts will keep rising; revisit the trend in Eureka once those years are more complete.
Explore the live trend in EurekaCommon questions about hydrolyzed and hypoallergenic formula patents
Within the 217 records in this dataset, a single assignee leads with 78 records, more than four times the fifth-place count of 17. The top five assignees combined account for 173 records, 79.7% of the total, so the field is heavily concentrated at the top with a long tail of smaller filers behind it. Anyone entering this space should expect the leading assignee's portfolio to touch most core hydrolysis and taste-masking methods.
The largest technology classes in the dataset are foods and non-alcoholic beverages (A23L, 75.1% of records) and proteins and food peptides (A23J, 56.2%), which together point to enzymatic protein hydrolysis and the resulting peptide profile as the central technical problem. A recurring secondary problem, illustrated by the representative filing in this dataset, is that hydrolysis reduces allergenicity but produces bitter peptides that require separate taste-masking or pH-adjustment methods. Medicinal-preparation claims (A61K, 47.0%) also appear often, showing many filings are framed with a therapeutic or clinical angle rather than purely as food processing.
Filing activity peaked so far in 2019 at 33 records, and growth cannot be reliably computed for the most recent years because publication typically lags filing by roughly 18 months. That means 2024-2026 figures in any dataset will look artificially low and should not be read as a genuine slowdown. A fair read of momentum requires waiting for those later years to finish publishing before drawing conclusions.
The technology composition shows heavier claim density in core hydrolysis and food-processing classes (A23L, A23J) than in areas like clinical tolerance data used to support labelling claims or animal-feed adaptations of hydrolysate methods (A23K, 18.4% of records). Enzyme selection specifically targeted at reducing residual allergenicity, rather than general hydrolysis, also shows comparatively thinner coverage relative to the core claim territory. These narrower, clinically-grounded angles are the more realistic places to stake a defensible first claim given how concentrated the core methods already are.
Among the receiving offices captured in this dataset, Europe (EPO) leads with 26 filings, followed by the United States with 23 and Australia with 21; WIPO (PCT) filings account for 14. This spread suggests applicants in this field are pursuing multi-jurisdiction protection through both regional and international routes rather than concentrating filings in a single office. Counsel evaluating freedom to operate should check coverage across at least these leading offices rather than assuming a single-jurisdiction search is sufficient.
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Disclaimer. This page is generated from Patsnap Eureka data drawn from a limited snapshot of global patent and scientific-literature records, and is provided for general information and reference only.
Patent data carries inherent limitations: recent filings (typically the most recent 18–24 months) are under-counted due to standard publication lag; counts may be reported at either a patent-family or a patent-record basis and are not always directly comparable; classification, applicant-name, and citation data may contain errors, duplicates, or omissions; and the underlying search query defines and constrains the scope shown. As a result, the analysis may be incomplete or inaccurate and may not reflect the full technology landscape.
Nothing on this page constitutes an exhaustive prior-art, novelty, freedom-to-operate, or validity search, nor does it constitute legal, financial, investment, or professional advice, and it should not be relied upon as such. Any patent, commercial, or strategic decision should be verified independently and reviewed with qualified patent, legal, and domain professionals. Patsnap makes no warranties, express or implied, as to the accuracy, completeness, or fitness for any particular purpose of the information presented.
Machine translation. Assignee and organisation names originally recorded in Chinese, Japanese or Korean have been rendered into English by an AI translation step so that the tables stay readable. These renderings are best-effort and may not match a company’s registered English name; the original name is what the underlying patent record carries, and it is what any Eureka query launched from this page uses.