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Hydrolyzed Formula Patents: Top Companies & Filing Trends 2026

Hydrolyzed Formula Patents: Top Companies & Filing Trends 2026
https://www.patsnap.com/resources/blog/rd-blog/hydrolyzed-and-hypoallergenic-formulas-patent-landscape/ · Patsnap · data cut-off 2026-07-31 · downloaded from the live page
Nutrition Products · Patent Landscape 2026
Hydrolyzed and Hypoallergenic Formula Patents: Who Holds the Ground
  • 79.7% concentration. The top five assignees account for 173 of 217 records in scope, leaving a thin tail behind them.
  • Peak filing year already behind us. Activity crested in 2019 at 33 records, with the most recent years still filling in behind the publication lag.
  • Protein chemistry dominates the claim map. A23J peptide and protein classes touch 56.2% of records, well ahead of the dairy-specific A23C class at 24.0%.
Get a prior-art report on your approach
217
Published Records
80%
Top-5 Share of All Records
EP
Leading Jurisdiction
32
Active Filers Ranked

Top-5 share is the combined record count of the five largest assignees divided by all 217 records in scope (CR5), not by the ranked leaders only.

Published byPatsnap Research··7 min readSourced from Patsnap Eureka
Field Overview

What the hydrolyzed and hypoallergenic formula patent record shows

Hydrolyzed and hypoallergenic infant formula sits at the intersection of protein chemistry and clinical nutrition: enzymatic hydrolysis breaks intact milk proteins into smaller peptides to reduce residual allergenicity, while formulators separately fight the bitterness those same peptides introduce. The patent record in scope, 217 published records from 2015 through the middle of 2026, tracks claims across peptide weight control, enzyme selection, taste-masking, and the clinical tolerance data used to support labelling claims.

Filing concentrates hard at the top of the assignee ranking, and the technology composition shows protein and peptide chemistry (A23J, C07K) sitting alongside medicinal-preparation claims (A61K, A61P) more often than dairy-specific processing (A23C) alone, which points to a field increasingly argued on biochemical and clinical grounds rather than pure food processing.

Filing activity and technology composition, 2015–2026
  1. 1SOCIETE DES PRODUITS NESTLE SA78
  2. 2DSM IP ASSETS BV37
  3. 3MJN US HOLDINGS LLC22
  4. 4NV NUTRICIA19
  5. 5JOHNSON MEAD NUTRITION CO17
  6. 6NESTEC SA17
  7. 7MILK CARE CO INC12
  8. 8DSM NV4
  9. 9EDENS LUPPO4
  10. 10Societe des Produits Nestle SA3
Source: Patsnap Eureka. Assignee ranking and totals. Derived from a Patsnap search on Hydrolyzed and Hypoallergenic Formulas covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP

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The Data

Filing trend and technology composition

Two views of the same 217-record dataset: filing activity by year, and where those records sit across IPC subclasses. Because a single record can carry several IPC codes, the class shares below add up to well over 100% of the record total.

Filing trend, 2015–2026

Filings peaked in 2019 at 33 records. Recent years understate true activity because publication typically lags filing by around 18 months, so 2025-2026 figures will keep rising as later-filed applications publish.

Filing trend, 2015–202601020304002017201833201920202021202220232024202502026Most recent year is partial — publication lag means later filings are not yet visible.

Technology composition by IPC subclass

A23L (foods and non-alcoholic beverages) touches 75.1% of the 217 records, and A23J (proteins and food peptides) touches 56.2%. Medicinal-preparation claims under A61K appear in 47.0% of records, showing how often formula claims are framed with a therapeutic rather than purely nutritional angle.

Technology composition by IPC subclassA23L · Foods & non-alcoholic beverages16375.1%A23J · Proteins & food peptides12256.2%A61K · Medicinal preparations10247.0%A61P · Therapeutic activity of compou…5525.3%A23C · Dairy products5224.0%C12N · Microorganisms & genetic engin…4721.7%A23K · Animal feed4018.4%C07K · Peptides & proteins3817.5%Other12557.6%

Shares are the percentage of the 217 records in scope. A patent can carry several IPC classes, so the shares add up to more than 100%.

Source: Patsnap Eureka. Filing trend and technology composition. Derived from a Patsnap search on Hydrolyzed and Hypoallergenic Formulas covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.

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Key Patents

The most-cited records in this field

Representative Filing
US20090117256A12009-05-07

Method for decreasing bitterness and improving taste of protein-free and hydrolyzed infant formulas

MEAD JOHNSON NUTRITION COMPANY

The present invention relates to a method for decreasing the bitterness or improving the taste of a protein-free or hydrolyzed infant formula. The method comprises intermixing ingredients of the formula and adjusting the pH of the formula to between about 6.5 and about 7.2.Filed by Mead Johnson Nutrition Company, this record targets one of the field's persistent formulation problems: hydrolysis reduces allergenicity but generates bitter peptides, and pH adjustment during mixing is claimed as a fix.

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Highest-cited patent records in scope
#Publication no.Patent titleCitations
1WO2002045524A2Prolyl endoprotease from aspergillus niger138
2WO2000042863A1A hypoallergenic composition containing tolerogenic peptides inducing oral tolerance84
3US20040241664A1Protein Hydrolysates Enriched In Peptides Having A Carboxy Terminal Proline Residue79
4WO2002045523A2Protein hydrolysates enriched in peptides having a carboxy terminal proline residue64
5US20020037357A1Hypoallergenic composition containing tolerogenic peptides36
6US20040241791A1Protein hydrolysates enriched in peptides having a carboxy terminal proline residue29
7WO2012042013A1Milk-based protein hydrolysates and infant formulae and nutritional compositions made thereof27
8WO2015090347A1Newly identified peptides for use in the induction of oral tolerance in young mammals22
9US6737076B2Hypoallergenic composition containing tolerogenic peptides18
10US7309595B2Protein hydrolysates enriched in peptides having a carboxy terminal proline residue17

Citation counts inside a searched corpus favour older filings that have had more time to accumulate citations; treat them as a signal of influence on the field, not of current commercial relevance.

Each row carries its publication number; clicking a row searches Eureka by that number.

Source: Patsnap Eureka. Citation counts and representative records. Derived from a Patsnap search on Hydrolyzed and Hypoallergenic Formulas covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
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Insights

What the numbers mean for a filing decision

The dataset points to a field where a small group of assignees has already built dense claim coverage around core hydrolysis and taste-masking methods, while clinical-tolerance and labelling-support claims remain comparatively open.

Concentration
79.7%
of 217 records held by top 5

Five assignees hold most of the field

The leading assignee alone accounts for 78 records, and the top five combined reach 173 of the 217 records in scope. That leaves a long tail of single- or few-filing entrants competing for the remaining space.

Top 5 combined, 173 of 217 records
Technology mix
56.2%
of records touch A23J peptides

Peptide chemistry outweighs dairy processing

A23J protein and peptide claims appear in more records than A23C dairy-specific processing (24.0%), suggesting the active argument in recent filings is about peptide weight and enzyme selection rather than raw milk processing.

A23J 56.2% vs A23C 24.0% of 217 records
Filing pace
33
records in the peak year, 2019

Activity has already crested once

2019 remains the peak filing year so far, at 33 records. Because publication lags filing by roughly 18 months, the apparent decline into 2025-2026 is partly an artefact of that lag rather than a real drop in activity.

Peak year 2019, 33 records
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Eureka can read the same corpus for gaps instead of for coverage: under-claimed branches adjacent to hydrolyzed and hypoallergenic formulas, with the prior art for and against each one.

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Where filings cluster jointly
AssigneeCo-assigneeShared families
Societe des Produits Nestle SANestec SA6
DSM IP Assets B.V.EDENS LUPPO4
MAYNARD FRANCOISEPANCHAUD ALEXANDRE3
MAYNARD FRANCOISEMERCENIER ANNICK3
MAYNARD FRANCOISEBUREAU FRANZ ISABELLE3
MAYNARD FRANCOISEAFFOLTER MICHAEL3
DSM IP Assets B.V.VAN DER HOEVEN ROBERTUS ANTONIUS MIJNDERT2
DSM IP Assets B.V.HOEVEN VAN DER ROBERTUS ANTONIUS MIJNDERT2

Ten co-assignee pairs appear in the dataset, with the strongest pairing linked to a single corporate group filing jointly across related entities, and a second pairing linking an ingredients specialist to a smaller named co-filer.

Source: Patsnap Eureka. Co-assignee relationships and derived observations. Derived from a Patsnap search on Hydrolyzed and Hypoallergenic Formulas covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
Players

Who is filing, and where the field is still open

The ranked list covers 32 companies, the full set the data endpoint returns for this search, not a top-50 or top-100 cut. Momentum in the latest complete year is flat to zero across the leading names, consistent with the publication-lag effect rather than a slowdown in real filing activity.

Leader
78
records

A single assignee anchors the field

The leading assignee's 78 records is more than four times the fifth-place count of 17, and its filings run across bitterness reduction, enzyme selection and hypoallergenic formulation together rather than any single narrow claim area.

Leader 78 vs fifth place 17 records
Mid-tier
17
records at fifth place

A mid-tier cluster with real but smaller footprints

Fifth place sits at 17 records, still well ahead of the tenth-place count of 3, showing a fairly steep drop-off rather than a gradual taper across the ranked assignees.

Fifth place 17, tenth place 3 records
Reach
98.2%
of 217 records held by top 10

Almost the whole field sits in ten hands

The top 10 combined account for 213 of the 217 records in scope, 98.2% of the total. Anyone outside that group is filing into a field where the dominant claim territory is already staked out by a small number of firms.

Top 10 combined, 213 of 217 records
🔍
Under-claimed sub-areas worth a closer look
Branches where filing density is comparatively thin relative to the core hydrolysis and bitterness-masking claims
peptide weight-cutoff profilingenzyme selection for residual allergenicityclinical tolerance data for labelling claimsanimal-feed hydrolysate adaptationmicrobial enzyme production routes
Rank all filers by momentum →
Recent-year filing momentum by assignee
AssigneeRecent yearYoY
Societe des Produits Nestle SA0
DSM IP Assets B.V.0
Nestec SA0
Mead Johnson Nutrition Company0
N.V. Nutricia0
MJN US Holdings LLC0
Milk Care Co Inc0
MAYNARD FRANCOISE0
Source: Patsnap Eureka. Assignee-level momentum. Derived from a Patsnap search on Hydrolyzed and Hypoallergenic Formulas covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
What's Next

Where to take this next

The figures above describe where the field has been. Deciding where to file next means running the same questions against the live, unfiltered dataset.

Check freedom to operate against the leader's full claim set

With one assignee holding 78 of 217 records, a focused freedom-to-operate review of that portfolio alone will clear or flag most of the field's core hydrolysis and taste-masking claims.

Run an FTO check in Eureka

Track the under-claimed branches before they fill in

Clinical-tolerance and labelling-support claims show thinner coverage than core hydrolysis methods; monitoring new filings there early gives more room to stake out defensible claim language.

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Re-run the trend once later years finish publishing

Because publication lags filing by around 18 months, 2025-2026 filing counts will keep rising; revisit the trend in Eureka once those years are more complete.

Explore the live trend in Eureka
Source: Patsnap Eureka. Forward-looking reading of the same dataset. Derived from a Patsnap search on Hydrolyzed and Hypoallergenic Formulas covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
FAQ

Common questions about hydrolyzed and hypoallergenic formula patents

Answers are grounded in the same dataset. Derived from a Patsnap search on Hydrolyzed and Hypoallergenic Formulas covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP

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Disclaimer. This page is generated from Patsnap Eureka data drawn from a limited snapshot of global patent and scientific-literature records, and is provided for general information and reference only.

Patent data carries inherent limitations: recent filings (typically the most recent 18–24 months) are under-counted due to standard publication lag; counts may be reported at either a patent-family or a patent-record basis and are not always directly comparable; classification, applicant-name, and citation data may contain errors, duplicates, or omissions; and the underlying search query defines and constrains the scope shown. As a result, the analysis may be incomplete or inaccurate and may not reflect the full technology landscape.

Nothing on this page constitutes an exhaustive prior-art, novelty, freedom-to-operate, or validity search, nor does it constitute legal, financial, investment, or professional advice, and it should not be relied upon as such. Any patent, commercial, or strategic decision should be verified independently and reviewed with qualified patent, legal, and domain professionals. Patsnap makes no warranties, express or implied, as to the accuracy, completeness, or fitness for any particular purpose of the information presented.

Machine translation. Assignee and organisation names originally recorded in Chinese, Japanese or Korean have been rendered into English by an AI translation step so that the tables stay readable. These renderings are best-effort and may not match a company’s registered English name; the original name is what the underlying patent record carries, and it is what any Eureka query launched from this page uses.

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