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Run your analysis now →A data-driven look at capillary electrophoresis chip and lab-on-a-chip patents: who holds the most families, where filings concentrate by IPC class and jurisdiction, and where the claim space is still open.
Top-5 share = the 5 largest assignees ÷ all 220 records in scope (CR5), not the ranked leaders only.
This landscape maps 220 published records tied to capillary electrophoresis chips and adjacent lab-on-a-chip microfluidic devices, spanning filings from 2015 through the 2026 cut-off. The scope covers chip-integrated capillary electrophoresis apparatus, detection schemes built into microfluidic channels, and the fabrication and separation methods that support them. Patent families, not raw document counts, are the unit used for the assignee ranking, which reduces the distortion from continuation filings and multi-jurisdiction duplicates.
The filing trend, technology composition and receiving-office breakdown below are drawn directly from this record set. Because publication typically lags filing by around 18 months, the most recent year understates real filing activity and should be read as a floor, not a ceiling.
Two views of the same 220 records: how filing activity has moved year over year, and which IPC subclasses carry the claim density.
Filings ran from 4 in 2017 to a peak of 15 in 2018, then continued at a lower but persistent pace through to 4 in 2026 (partial year). The 2018 peak likely reflects an early wave of chip-integration filings; later years show no single dominant surge, consistent with a field where core detection methods were staked out early and later filings fill in variants.
G01N (material analysis and testing) appears in 74.5% of the 220 records, confirming that most claims are written around detection and measurement rather than the chip structure itself. C12Q (enzyme/DNA testing, 20.5%) and B01L (lab apparatus, 11.4%) are the next largest groups. B81B (MEMS structural devices, 5.9%) and C08F (addition polymers, 3.6%) are comparatively thin, which is worth noting for anyone filing on chip substrate or microstructure claims rather than the assay layered on top.
Shares are the percentage of the 220 records in scope. A patent can carry several IPC classes, so the shares add up to more than 100%.
This page is one run against one query. Ask Eureka your own question about lab-on-a-chip & microfluidics: capillary electrophoresis chip patent landscape and every answer comes back with the patent numbers behind it.
Try EurekaFiled by Tsinghua University and granted in 2009, this patent describes a three-layer chip: an upper channel layer with a microfluidic channel and electrode aperture for sample loading, a middle electrode layer that seals the channel into an intact capillary and supplies the electrophoresis voltage, and a lower heating layer that maintains a stable temperature gradient. The three layers are thermally conductive and bonded to one another.The claim structure ties detection (nucleotide/SNP genotyping) to a specific three-layer physical stack rather than to electrophoresis broadly — a distinction that matters for anyone assessing freedom to operate.


| # | Publication no. | Patent title | Citations |
|---|---|---|---|
| 1 | US6361671B1 | Microfabricated capillary electrophoresis chip and method for simultaneously detecting multiple redox labels | 339 |
| 2 | US6045676A | Electrochemical detector integrated on microfabricated capilliary electrophoresis chips | 169 |
| 3 | US5906723A | Electrochemical detector integrated on microfabricated capillary electrophoresis chips | 130 |
| 4 | WO2005094981A1 | Cyclic PCR system | 93 |
| 5 | US20060163069A1 | Universal interface for a micro-fluidic chip | 61 |
| 6 | US20130213811A1 | Microscale western blot | 42 |
| 7 | US20070009970A1 | Biological patterns for diagnosis and treatment of cancer | 40 |
| 8 | US20050244973A1 | Biological patterns for diagnosis and treatment of cancer | 39 |
| 9 | JP1999248678A | Capillary electrophoresis chip | 33 |
| 10 | WO2003102212A2 | In vitro evaluation of nucleic acid ligands | 31 |
Citation counts favour older records in any searched corpus; read them as a signal of influence on later filings, not as a measure of current commercial relevance.
Each row carries its publication number; clicking a row searches Eureka by that number.
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Run your analysis now →When it has to run inside your own pipeline.
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Browse MCP servers →Four read-outs from the dataset, aimed at where to file, who to watch, and what claim space is still open.
The leading assignee holds 25 records and the fifth-ranked holder 8, giving the top 5 a combined 33.6% of all 220 records in scope. That leaves two-thirds of filings spread across a long tail — enough headroom for a new entrant to establish a position without directly overlapping the largest holders, provided the claims are drawn narrowly enough to clear their prior art.
Three-quarters of records carry a G01N material-analysis classification, meaning most claim language sits on how the chip detects or measures rather than how it is built. B81B (MEMS structural devices) covers only 5.9% of records, and C08F (polymer substrates) just 3.6% — both comparatively open ground for structural or materials-focused filings.
China's 57 filings sit ahead of the United States at 42, with EPO and WIPO/PCT each at 28. For a company assessing enforcement or freedom-to-operate exposure, China and the US together account for the bulk of near-term risk, while EPO/WIPO filings mark where applicants are seeking broader regional coverage.
The most-cited record, on microfabricated capillary electrophoresis chips with simultaneous multi-label redox detection, carries 339 citations — well ahead of the next-most-cited records. High citation counts here mark early, foundational filings rather than current state of the art, since citation counts in any searched corpus accumulate in favour of older documents.
Eureka can read the same corpus for gaps instead of for coverage: under-claimed branches adjacent to lab-on-a-chip & microfluidics: capillary electrophoresis chip patent landscape, with the prior art for and against each one.
The dataset points to specific next steps depending on whether the goal is freedom-to-operate, portfolio strategy, or identifying open claim space.
Before drafting a detection-method claim, check it against the 74.5% of records already classified under G01N to identify what has actually been claimed versus assumed.
Explore the claim landscape in EurekaB81B and C08F sit well below the field average — worth a closer look for anyone filing on chip substrate, microstructure or polymer composition rather than the assay layered on top.
Run a white-space search in EurekaWith the top 5 holding 33.6% of records, watching their most recent publications is a faster way to anticipate where claim boundaries are moving than scanning the full long tail.
Set up assignee monitoring in EurekaThe dataset ranks 100 assignees across 220 records, with the leading holder at 25 records and the top 5 combined accounting for 33.6% of all records in scope. That leaves roughly two-thirds of filings spread across a long tail of universities, diagnostics companies and smaller entrants. No single company controls the field outright, but the leaders have enough density to shape freedom-to-operate analysis for anyone entering detection-method claims.
G01N (material analysis and testing) is by far the largest classification, appearing in 74.5% of the 220 records, followed by C12Q (enzyme and DNA testing) at 20.5% and B01L (lab apparatus) at 11.4%. This means most claims describe how the chip detects or measures a sample rather than the physical chip structure itself. Structural classifications such as B81B (MEMS devices, 5.9%) and C08F (polymer substrates, 3.6%) are comparatively thin, marking areas with less claim density.
China leads receiving-office volume with 57 filings, ahead of the United States at 42, and EPO and WIPO/PCT each at 28. Australia and Canada trail well behind at 11 and 10 respectively. For companies assessing where enforcement risk or licensing opportunity is concentrated, China and the US together represent the majority of near-term exposure in this dataset.
Filing activity peaked in 2018 at 15 records and has since continued at a lower, fairly steady pace, with 4 records recorded in 2026 so far. Because publication lags filing by roughly 18 months, the most recent two to three years are understated in any patent count and should not be read as a genuine slowdown. A reliable growth rate cannot be computed from this record set once that lag is accounted for.
US7527719B2, assigned to Tsinghua University, claims a three-layer capillary electrophoresis chip: an upper microfluidic channel layer, a middle electrode layer that seals the channel and supplies electrophoresis voltage, and a lower heating layer that maintains a temperature gradient. It ties nucleotide and single-nucleotide-polymorphism detection to that specific physical stack rather than to capillary electrophoresis in general. A design that detects SNPs through a different layer arrangement, heating method or electrode placement would sit outside its literal claim scope, though a full freedom-to-operate check should still compare it against the broader G01N-classified filings in the dataset.
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Disclaimer. This page is generated from Patsnap Eureka data drawn from a limited snapshot of global patent and scientific-literature records, and is provided for general information and reference only.
Patent data carries inherent limitations: recent filings (typically the most recent 18–24 months) are under-counted due to standard publication lag; counts may be reported at either a patent-family or a patent-record basis and are not always directly comparable; classification, applicant-name, and citation data may contain errors, duplicates, or omissions; and the underlying search query defines and constrains the scope shown. As a result, the analysis may be incomplete or inaccurate and may not reflect the full technology landscape.
Nothing on this page constitutes an exhaustive prior-art, novelty, freedom-to-operate, or validity search, nor does it constitute legal, financial, investment, or professional advice, and it should not be relied upon as such. Any patent, commercial, or strategic decision should be verified independently and reviewed with qualified patent, legal, and domain professionals. Patsnap makes no warranties, express or implied, as to the accuracy, completeness, or fitness for any particular purpose of the information presented.
Machine translation. Assignee and organisation names originally recorded in Chinese, Japanese or Korean have been rendered into English by an AI translation step so that the tables stay readable. These renderings are best-effort and may not match a company's registered English name; the original name is what the underlying patent record carries, and it is what any Eureka query launched from this page uses.