https://www.patsnap.com/resources/blog/rd-blog/lab-on-a-chip-and-microfluidics-capillary-electrophoresis-chip-patent-landscape-patent-landscape/ · Patsnap · data cut-off 2026-08-31 · downloaded from the live page
Patent Landscape · Lab-on-a-Chip & Microfluidics
Capillary electrophoresis chip patents: who holds the claims and where the field is still open

A data-driven look at capillary electrophoresis chip and lab-on-a-chip patents: who holds the most families, where filings concentrate by IPC class and jurisdiction, and where the claim space is still open.

220
Published Records
34%
Top-5 Share of All Records
CN
Leading Jurisdiction
100
Active Filers Ranked

Top-5 share = the 5 largest assignees ÷ all 220 records in scope (CR5), not the ranked leaders only.

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Published byPatsnap Research··6 min readSourced from Patsnap Eureka
Overview

What this landscape covers

This landscape maps 220 published records tied to capillary electrophoresis chips and adjacent lab-on-a-chip microfluidic devices, spanning filings from 2015 through the 2026 cut-off. The scope covers chip-integrated capillary electrophoresis apparatus, detection schemes built into microfluidic channels, and the fabrication and separation methods that support them. Patent families, not raw document counts, are the unit used for the assignee ranking, which reduces the distortion from continuation filings and multi-jurisdiction duplicates.

The filing trend, technology composition and receiving-office breakdown below are drawn directly from this record set. Because publication typically lags filing by around 18 months, the most recent year understates real filing activity and should be read as a floor, not a ceiling.

Filing activity and technology composition, 2015–2026
  1. 1RGT UNIV OF CALIFORNIA25
  2. 2NORTHWESTERN UNIV22
  3. 3TSINGHUA UNIVERSITY10
  4. 4NINGBO HEALTH GENE TECHNOLOGIES CO LTD9
  5. 5ZHEJIANG UNIV8
  6. 6AGILENT TECHNOLOGIES INC8
  7. 7GLAXOSMITHKLINE BIOLOGICALS SA7
  8. 8FUJIFILM WAKO PURE CHEMICAL CORP7
  9. 9AST MANAGEMENT6
  10. 10CAPITALBIO CORP6
Source: Patsnap Eureka. Assignee ranking and totals. Derived from a Patsnap search on Lab-on-a-Chip & Microfluidics: Capillary Electrophoresis Chip Patent Landscape covering 2015–2026, data cut-off 2026-08-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
The data

Filing trend and technology composition

Two views of the same 220 records: how filing activity has moved year over year, and which IPC subclasses carry the claim density.

Filing trend, 2017–2026

Filings ran from 4 in 2017 to a peak of 15 in 2018, then continued at a lower but persistent pace through to 4 in 2026 (partial year). The 2018 peak likely reflects an early wave of chip-integration filings; later years show no single dominant surge, consistent with a field where core detection methods were staked out early and later filings fill in variants.

Filing trend, 2017–2026048111542017152018201920202021202220232024202542026Most recent year is partial — publication lag means later filings are not yet visible.

Technology composition by IPC subclass

G01N (material analysis and testing) appears in 74.5% of the 220 records, confirming that most claims are written around detection and measurement rather than the chip structure itself. C12Q (enzyme/DNA testing, 20.5%) and B01L (lab apparatus, 11.4%) are the next largest groups. B81B (MEMS structural devices, 5.9%) and C08F (addition polymers, 3.6%) are comparatively thin, which is worth noting for anyone filing on chip substrate or microstructure claims rather than the assay layered on top.

Technology composition by IPC subclassG01N · Material analysis & testing16474.5%C12Q · Measuring & testing involving …4520.5%B01L · Lab apparatus2511.4%B01D · Separation processes (filtrati…2210.0%B81B · Microstructural devices (MEMS)135.9%C08F · Addition polymers (vinyl etc.)83.6%C12N · Microorganisms & genetic engin…52.3%A61K · Medicinal preparations31.4%Other3817.3%

Shares are the percentage of the 220 records in scope. A patent can carry several IPC classes, so the shares add up to more than 100%.

Source: Patsnap Eureka. Filing trend and technology composition. Derived from a Patsnap search on Lab-on-a-Chip & Microfluidics: Capillary Electrophoresis Chip Patent Landscape covering 2015–2026, data cut-off 2026-08-31. Counts reflect published records only and shift as new filings publish.

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Key patents

Representative and most-cited filings

Representative filing
US7527719B22009-05-05

US7527719B2 — Capillary electrophoresis chip apparatus for detecting nucleotide polymorphism and single nucleotide polymorphism

TSINGHUA UNIVERSITY

Filed by Tsinghua University and granted in 2009, this patent describes a three-layer chip: an upper channel layer with a microfluidic channel and electrode aperture for sample loading, a middle electrode layer that seals the channel into an intact capillary and supplies the electrophoresis voltage, and a lower heating layer that maintains a stable temperature gradient. The three layers are thermally conductive and bonded to one another.The claim structure ties detection (nucleotide/SNP genotyping) to a specific three-layer physical stack rather than to electrophoresis broadly — a distinction that matters for anyone assessing freedom to operate.

US7527719B2 — patent drawing 1US7527719B2 — patent drawing 2
View full record
Most-cited records in this landscape
#Publication no.Patent titleCitations
1US6361671B1Microfabricated capillary electrophoresis chip and method for simultaneously detecting multiple redox labels339
2US6045676AElectrochemical detector integrated on microfabricated capilliary electrophoresis chips169
3US5906723AElectrochemical detector integrated on microfabricated capillary electrophoresis chips130
4WO2005094981A1Cyclic PCR system93
5US20060163069A1Universal interface for a micro-fluidic chip61
6US20130213811A1Microscale western blot42
7US20070009970A1Biological patterns for diagnosis and treatment of cancer40
8US20050244973A1Biological patterns for diagnosis and treatment of cancer39
9JP1999248678ACapillary electrophoresis chip33
10WO2003102212A2In vitro evaluation of nucleic acid ligands31

Citation counts favour older records in any searched corpus; read them as a signal of influence on later filings, not as a measure of current commercial relevance.

Each row carries its publication number; clicking a row searches Eureka by that number.

Source: Patsnap Eureka. Citation counts and representative records. Derived from a Patsnap search on Lab-on-a-Chip & Microfluidics: Capillary Electrophoresis Chip Patent Landscape covering 2015–2026, data cut-off 2026-08-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
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Insights

What the numbers mean for a filing decision

Four read-outs from the dataset, aimed at where to file, who to watch, and what claim space is still open.

Concentration
33.6% of 220 records
held by top 5 assignees

The top of the field is concentrated, not locked

The leading assignee holds 25 records and the fifth-ranked holder 8, giving the top 5 a combined 33.6% of all 220 records in scope. That leaves two-thirds of filings spread across a long tail — enough headroom for a new entrant to establish a position without directly overlapping the largest holders, provided the claims are drawn narrowly enough to clear their prior art.

Based on the 220-record assignee ranking
Claim density
74.5% G01N vs 5.9% B81B
detection vs. device-structure claims

Detection methods are crowded; chip microstructure is not

Three-quarters of records carry a G01N material-analysis classification, meaning most claim language sits on how the chip detects or measures rather than how it is built. B81B (MEMS structural devices) covers only 5.9% of records, and C08F (polymer substrates) just 3.6% — both comparatively open ground for structural or materials-focused filings.

IPC subclass shares, 220 records in scope
Jurisdiction
China 57 · US 42 · EPO 28 · WIPO 28
receiving-office filings

China now leads receiving-office volume

China's 57 filings sit ahead of the United States at 42, with EPO and WIPO/PCT each at 28. For a company assessing enforcement or freedom-to-operate exposure, China and the US together account for the bulk of near-term risk, while EPO/WIPO filings mark where applicants are seeking broader regional coverage.

Receiving office counts across the record set
Influence
339 citations
on the most-cited record

Foundational detector patents still anchor later filings

The most-cited record, on microfabricated capillary electrophoresis chips with simultaneous multi-label redox detection, carries 339 citations — well ahead of the next-most-cited records. High citation counts here mark early, foundational filings rather than current state of the art, since citation counts in any searched corpus accumulate in favour of older documents.

Most-cited records in the 220-record set
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Looking for what nobody has claimed yet?

Eureka can read the same corpus for gaps instead of for coverage: under-claimed branches adjacent to lab-on-a-chip & microfluidics: capillary electrophoresis chip patent landscape, with the prior art for and against each one.

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Source: Patsnap Eureka. Co-assignee relationships and derived observations. Derived from a Patsnap search on Lab-on-a-Chip & Microfluidics: Capillary Electrophoresis Chip Patent Landscape covering 2015–2026, data cut-off 2026-08-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
What's next

Where to take this analysis

The dataset points to specific next steps depending on whether the goal is freedom-to-operate, portfolio strategy, or identifying open claim space.

Map claims against the crowded G01N cluster

Before drafting a detection-method claim, check it against the 74.5% of records already classified under G01N to identify what has actually been claimed versus assumed.

Explore the claim landscape in Eureka

Assess the under-claimed structural branches

B81B and C08F sit well below the field average — worth a closer look for anyone filing on chip substrate, microstructure or polymer composition rather than the assay layered on top.

Run a white-space search in Eureka

Track the leading assignees' recent filings

With the top 5 holding 33.6% of records, watching their most recent publications is a faster way to anticipate where claim boundaries are moving than scanning the full long tail.

Set up assignee monitoring in Eureka
Source: Patsnap Eureka. Forward-looking reading of the same dataset. Derived from a Patsnap search on Lab-on-a-Chip & Microfluidics: Capillary Electrophoresis Chip Patent Landscape covering 2015–2026, data cut-off 2026-08-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
FAQ

Common questions on this landscape

Answers are grounded in the same dataset. Derived from a Patsnap search on Lab-on-a-Chip & Microfluidics: Capillary Electrophoresis Chip Patent Landscape covering 2015–2026, data cut-off 2026-08-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP

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Disclaimer. This page is generated from Patsnap Eureka data drawn from a limited snapshot of global patent and scientific-literature records, and is provided for general information and reference only.

Patent data carries inherent limitations: recent filings (typically the most recent 18–24 months) are under-counted due to standard publication lag; counts may be reported at either a patent-family or a patent-record basis and are not always directly comparable; classification, applicant-name, and citation data may contain errors, duplicates, or omissions; and the underlying search query defines and constrains the scope shown. As a result, the analysis may be incomplete or inaccurate and may not reflect the full technology landscape.

Nothing on this page constitutes an exhaustive prior-art, novelty, freedom-to-operate, or validity search, nor does it constitute legal, financial, investment, or professional advice, and it should not be relied upon as such. Any patent, commercial, or strategic decision should be verified independently and reviewed with qualified patent, legal, and domain professionals. Patsnap makes no warranties, express or implied, as to the accuracy, completeness, or fitness for any particular purpose of the information presented.

Machine translation. Assignee and organisation names originally recorded in Chinese, Japanese or Korean have been rendered into English by an AI translation step so that the tables stay readable. These renderings are best-effort and may not match a company's registered English name; the original name is what the underlying patent record carries, and it is what any Eureka query launched from this page uses.