Sample Preparation for Structural Biology Patents: Leaders & Trends 2026
Sample Preparation for Structural Biology: Patents, Leading Filers and Where the Field Is Still Open
One filer leads with 11 records against a long tail down to single-digit and single-filing entrants across the 22 ranked assignees. Filings ran flat through the mid-2010s, rose to a peak of 4 records in 2019, then declined; the figure the dataset supports directly is a -100% change from 2021 (3 records) to 2024 (0 records), the last year with complete data before publication lag distorts the count.
- 1EGOROVA ZACHERNYUK TATIANA A11
- 2MASSACHUSETTS INST OF TECH8
- 3ENCODIA INC5
- 4WISCONSIN ALUMNI RES FOUND4
- 5DANA FARBER CANCER INSTITUTE INC4
See the full sample preparation for structural biology analysis in Eureka
- The complete ranking, not just the top five
- Every IPC branch with its share of the corpus
- The most-cited records, and where claim space is still thin
Common questions about this landscape
Who holds the most patents in protein sample preparation for structural biology?
The ranked dataset of 22 assignees shows one filer clearly ahead with 11 records, compared with 4 for the fifth-place holder and 3 for the tenth. That is a steep drop-off rather than a gradual one, meaning the field has a single dominant filer surrounded by a long tail of smaller and single-filing entrants. Anyone doing freedom-to-operate work in this space should review that leading portfolio first, since it accounts for a disproportionate share of the ranked activity.
Is patent filing in this field growing or shrinking?
Filing peaked at 4 records in 2019 and then declined, with the dataset showing a -100% change from 2021 (3 records) to 2024 (0 records) — the most recent year that can be treated as complete. Because publication typically lags actual filing by about 18 months, the 2025 and 2026 figures are still incomplete and should not be read as proof the field has gone quiet. A clearer read on the current trajectory will only be possible once those later years finish publishing.
What kinds of methods are actually being claimed?
The largest cluster, G01N (material analysis & testing), covers 55.6% of the 36 records, closely followed by C12N (microorganisms & genetic engineering) at 44.4%. Peptide and protein claims under C07K and fermentation/enzymatic synthesis claims under C12P each appear in 30.6% of records. Smaller clusters — medicinal preparations, general organic chemistry, acyclic compounds and nucleic acid chemistry — each sit around 11.1%, marking narrower, less-occupied branches of the field.
Disclaimer. This analysis is based on Patsnap Eureka data drawn from a limited snapshot of global patent records and is provided for general information and reference only. Patent data carries inherent limitations — recent filings are under-counted because of publication lag, counts may be on a record or family basis, classification and applicant-name data may contain errors or duplicates, and the underlying search query defines the scope shown — so the analysis may be incomplete or inaccurate and may not reflect the full technology landscape.
Nothing here is an exhaustive prior-art, novelty, freedom-to-operate or validity search, nor does it constitute legal, financial or professional advice, and it should not be relied upon as such. Verify independently and review with qualified patent and legal professionals before acting on it.
Method: Filing trend and technology composition. Derived from a Patsnap search on Sample Preparation for Structural Biology covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish. Every share divides by all records in scope. Data: Patsnap Eureka. See the full landscape report.