Sequencing Library Preparation Patents: Who Leads and Where Claims Are Open
28.7% concentration at the top. The five leading assignees hold 848 of the 2,950 records in scope, but a long tail of single- and few-filing entrants fills out the rest of the ranking. Filings ran from 206 in 2017 to a peak of 329 in 2022, then eased to 186 by 2024 — a -29% move from 2021's 261. Treat 2025 and 2026 as undercounted rather than as evidence of a continued decline, since publication typically lags filing by around 18 months.
- 1FOUNDATION MEDICINE INC12.3%
- 2THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV5.2%
- 3COMPLETE GENOMICS INC4.7%
- 4DOVETAIL GENOMICS LLC3.4%
- 5NATERA INC3.2%
See the full sequencing library preparation analysis in Eureka
- The complete ranking, not just the top five
- Every IPC branch with its share of the corpus
- The most-cited records, and where claim space is still thin
Common questions on sequencing library preparation patents
How many patents exist for sequencing library preparation?
The dataset used for this landscape contains 2,950 published patent records dated between 2015 and the 2026 cut-off, covering fragmentation, adapter ligation, amplification and related quality-control methods. This counts individual published records rather than distinct patent families, though the assignee ranking in this dataset is also expressed in the same 2,950-record terms. Because publication lags filing by roughly 18 months, the true count for 2025 and 2026 filings will be higher than currently shown.
Who are the leading patent holders in sequencing library preparation?
The leading assignee holds 363 of the 2,950 records in scope, with the top five combined holding 848 records (28.7% of the field) and the top ten holding 1,194 records (40.5%). Below that, the ranking drops off quickly — fifth place sits at 93 records and tenth at 57 — leaving a long tail of assignees with far fewer filings each. Several of the historically largest filers show sharply negative year-over-year momentum in the most recent data, so current filing rank and historical filing rank are not the same thing.
Is the sequencing library preparation patent field still growing?
Filing activity peaked in 2022 at 329 records and had fallen to 186 by 2024, a -29% move from 2021's 261 filings — the last year-over-year comparison that uses two complete years. That is a genuine pullback from an unusually active period rather than continued decline into 2025-2026, since those years are still under-published due to the typical 18-month lag between filing and publication. Whether the field resumes growth or settles at a lower rate will only be clear once 2025-2026 data matures.
Disclaimer. This analysis is based on Patsnap Eureka data drawn from a limited snapshot of global patent records and is provided for general information and reference only. Patent data carries inherent limitations — recent filings are under-counted because of publication lag, counts may be on a record or family basis, classification and applicant-name data may contain errors or duplicates, and the underlying search query defines the scope shown — so the analysis may be incomplete or inaccurate and may not reflect the full technology landscape.
Nothing here is an exhaustive prior-art, novelty, freedom-to-operate or validity search, nor does it constitute legal, financial or professional advice, and it should not be relied upon as such. Verify independently and review with qualified patent and legal professionals before acting on it.
Method: Filing trend and technology composition. Derived from a Patsnap search on Sequencing Library Preparation covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish. Every share divides by all records in scope. Data: Patsnap Eureka. See the full landscape report.