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Sorbent Dialysate Regeneration Patents: Leaders & White Space 2026

Sorbent Dialysate Regeneration Patents: Leaders & White Space 2026
https://www.patsnap.com/resources/blog/rd-blog/sorbent-dialysate-regeneration-patent-landscape/ · Patsnap · data cut-off 2026-07-31 · downloaded from the live page
Patent Landscape · Blood Purification
Sorbent Dialysate Regeneration Patents: Who Holds the Manifold Claims
  • Three assignees account for all 23 records in scope, with no long tail of smaller filers left outstanding once the ranked leaders are counted.
  • Filing activity peaked at 14 records in 2021 and fell to 1 by 2024, a -93% drop across that three-year span that predates the usual 18-month publication lag.
  • The two most-cited records in the set are manifold patents for wearable artificial kidneys, cited far ahead of any toxin-removal-loop filing that has followed them.
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23
Published Records
-93%
Filing Growth 2021→2024
EP
Leading Jurisdiction
2021
Peak Filing Year

Filing growth compares 2021 (14 records) with 2024 (1) — a three-year span. 2024 is the most recent year we treat as complete: publication lags filing by roughly 18 months, so 2025 onwards are still filling in and any growth rate that ends there would understate the field.

Published byPatsnap Research··6 min readSourced from Patsnap Eureka
Field Overview

What sorbent dialysate regeneration covers

Sorbent dialysate regeneration replaces continuous fresh-dialysate supply with a cartridge system that strips urea, ammonia and other toxins from spent dialysate so a small volume of fluid can be recirculated. The approach underpins wearable and portable artificial kidney designs, where cartridge capacity, urease layer chemistry and zirconium phosphate sorbent stages determine how long a device can run before ammonia breakthrough forces a cartridge change. Claims in this space cluster around the fluid manifold that routes dialysate through sorbent stages, the sorbent chemistry itself, and the electrolyte rebalancing needed to correct what the sorbent bed strips out along with the toxins.

The dataset in scope covers 23 published records filed between 2015 and 2026, concentrated overwhelmingly in devices-for-body-fluids classifications with a substantial secondary presence in catalysis and separation-process filings.

Filing activity, 2015-2026
  1. 1Temasek Polytechnic14
  2. 2University of Washington5
  3. 3Fresenius Medical Care Holdings, Inc.4
Source: Patsnap Eureka. Assignee ranking and totals. Derived from a Patsnap search on Sorbent Dialysate Regeneration covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP

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The Data

Filing trend and technology composition

Two views of the same 23 records: how filing activity has moved year over year, and which IPC subclasses the claims sit in.

A sharp peak, then a pullback

Filings were essentially flat through 2017, built to a peak of 14 records in 2021, then fell to 1 by 2024 — a -93% move across that three-year span. Because publication lags filing by roughly 18 months, 2025 and 2026 records are still arriving and should not yet be read as a continued decline.

A sharp peak, then a pullback048111502017201820192020142021202220232024202502026Most recent year is partial — publication lag means later filings are not yet visible.

Concentrated in body-fluid devices, with catalysis a strong second

Every record in scope carries an A61M (devices for body fluids) classification. B01J (chemical and physical processes, catalysis) appears in 13 of the 23 records, or 56.5%, reflecting how much of the inventive work sits in sorbent chemistry rather than the fluid circuit alone. B01D (separation processes, including filtration) appears in 7 records, 30.4%, pointing to a smaller but active seam around membrane and filtration stages.

Concentrated in body-fluid devices, with catalysis a strong secondA61M · Devices for body fluids23100.0%B01J · Chemical/physical processes & …1356.5%B01D · Separation processes (filtrati…730.4%

Shares are the percentage of the 23 records in scope. A patent can carry several IPC classes, so the shares add up to more than 100%.

Source: Patsnap Eureka. Filing trend and technology composition. Derived from a Patsnap search on Sorbent Dialysate Regeneration covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.

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Key Patents

The records shaping this field

Representative Filing
US20240238493A12024-07-18

Dialysis system incorporating a toxin-removal loop (US20240238493A1, University of Washington, 2024)

UNIVERSITY OF WASHINGTON

A protected fluid circuit uses osmotic or otherwise urea-selective membranes to move urea from spent dialysate to a separate removal side without direct contact, in a forward-osmosis geometry. Paired with an oxidation unit, the design aims for high selective urea flux while balancing patient fluid levels through controlled water evaporation across a vapor-permeable membrane, and protecting the patient-side dialysate/blood loop from oxidation by-products.Abstract text drawn directly from the published filing.

US20240238493A1 — patent drawing 1US20240238493A1 — patent drawing 2
View full record
Most-cited records in scope
#Publication no.Patent titleCitations
1US20150314056A1Manifold For Wearable Artificial Kidney19
2WO2014099631A1Manifold for wearable artificial kidney11
3WO2022216604A1Dialysis system incorporating a toxin-removal loop2
4US20240238493A1Dialysis system incorporating a toxin-removal loop1
5WO2021211060A1Dialysate regenerator comprising reversible retainer1

Citation counts reward older filings that have had more time to accumulate references — read them as a signal of influence on the field's history, not of what matters most today.

Publication numbers are shown where the record carries one (5 of 5 rows); clicking a row searches Eureka by that number.

Source: Patsnap Eureka. Citation counts and representative records. Derived from a Patsnap search on Sorbent Dialysate Regeneration covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
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Insights

What the numbers mean for a filing decision

Three findings that shape where a new filing would land relative to existing claims.

Concentration
23 = 100.0%
of all 23 records held by the top 3 assignees

No long tail left to map

The top 3 and top 5 figures are identical because only three assignees appear in the ranking at all, and together they account for every record in scope. There is no fragmented periphery of single-filing entrants to watch here — the field is small and already claimed by a short list of organisations.

Assignee ranking, all 23 records
Momentum
-93%
2021 (14 records) to 2024 (1 record)

A sharp pullback after a 2021 peak

Filing activity built steadily to a peak of 14 records in 2021, then dropped to 1 by 2024. That decline sits well before the 18-month publication lag would distort the picture, so it reflects a real reduction in disclosed activity rather than an artefact of recent filings still working through the pipeline.

Filing trend, 2015-2026
Citation weight
19 citations
highest count in the set, on a wearable-artificial-kidney manifold

Influence sits with the manifold, not the sorbent chemistry

The two most-cited records in the dataset both describe manifolds for wearable artificial kidneys rather than sorbent cartridge chemistry itself. Newer toxin-removal-loop filings have accumulated only a fraction of that citation count so far, which is consistent with their more recent publication dates rather than lower relevance.

Most-cited records table
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Looking for what nobody has claimed yet?

Eureka can read the same corpus for gaps instead of for coverage: under-claimed branches adjacent to sorbent dialysate regeneration, with the prior art for and against each one.

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Source: Patsnap Eureka. Co-assignee relationships and derived observations. Derived from a Patsnap search on Sorbent Dialysate Regeneration covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
Players

Who holds the claims

Three assignees make up the entire ranked field. None shows filing activity in the latest tracked year, consistent with the broader pullback since the 2021 peak.

Leader
14 records
records attributed to the leading assignee

One organisation holds close to two-thirds of the set

The leading assignee's 14 records against a field of 23 total gives it a commanding share of everything in scope, well ahead of the other two ranked organisations combined.

Assignee ranking
Academic presence
2 of 3
ranked assignees are universities

University research drives a meaningful share of filings

Two of the three ranked assignees are academic institutions rather than device manufacturers, reflecting how much of the sorbent-regeneration work, particularly on membrane geometry and toxin-removal loops, is still originating in research settings rather than product lines.

Assignee ranking
Industry anchor
1 of 3
ranked assignees is a commercial dialysis provider

A single commercial player anchors the field

Only one of the three ranked assignees is a commercial dialysis-equipment or services company, meaning most of the claim space in this dataset is held by parties whose incentive is publication and licensing rather than direct product defence.

Assignee ranking
🔍
Under-claimed sub-areas worth checking before filing
None of these appear as a dedicated claim focus in the current 23-record set.
Ammonia breakthrough sensingCartridge capacity forecasting algorithmsElectrolyte rebalancing dosing controlCost-per-session optimisation logicUrease layer degradation monitoring
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Recent-year filing momentum by assignee
AssigneeRecent yearYoY
Temasek Polytechnic0
University of Washington0
Fresenius Medical Care Holdings, Inc.0
Source: Patsnap Eureka. Assignee-level momentum. Derived from a Patsnap search on Sorbent Dialysate Regeneration covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
What's Next

Where to take this analysis

The dataset points to a small, concentrated field with a clear citation leader and a recent pullback in disclosed activity — but concentration in three assignees does not mean every sub-area is covered.

Check the under-claimed sub-areas before drafting

Ammonia-breakthrough sensing, cartridge-capacity forecasting and electrolyte-rebalancing dosing control do not appear as dedicated claim focuses in this set, which makes them worth a freedom-to-operate check before assuming they are occupied.

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Track whether the 2021 peak repeats as later years fill in

2025 and 2026 records are still arriving under the normal publication lag, so the apparent decline after 2021 needs revisiting once those years are more complete.

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Source: Patsnap Eureka. Forward-looking reading of the same dataset. Derived from a Patsnap search on Sorbent Dialysate Regeneration covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
FAQ

Common questions on sorbent dialysate regeneration patents

Answers are grounded in the same dataset. Derived from a Patsnap search on Sorbent Dialysate Regeneration covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP

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Disclaimer. This page is generated from Patsnap Eureka data drawn from a limited snapshot of global patent and scientific-literature records, and is provided for general information and reference only.

Patent data carries inherent limitations: recent filings (typically the most recent 18–24 months) are under-counted due to standard publication lag; counts may be reported at either a patent-family or a patent-record basis and are not always directly comparable; classification, applicant-name, and citation data may contain errors, duplicates, or omissions; and the underlying search query defines and constrains the scope shown. As a result, the analysis may be incomplete or inaccurate and may not reflect the full technology landscape.

Nothing on this page constitutes an exhaustive prior-art, novelty, freedom-to-operate, or validity search, nor does it constitute legal, financial, investment, or professional advice, and it should not be relied upon as such. Any patent, commercial, or strategic decision should be verified independently and reviewed with qualified patent, legal, and domain professionals. Patsnap makes no warranties, express or implied, as to the accuracy, completeness, or fitness for any particular purpose of the information presented.

Machine translation. Assignee and organisation names originally recorded in Chinese, Japanese or Korean have been rendered into English by an AI translation step so that the tables stay readable. These renderings are best-effort and may not match a company’s registered English name; the original name is what the underlying patent record carries, and it is what any Eureka query launched from this page uses.

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