Spatial Proteomics Patents: Who Leads, Where the Gaps Are 2026
Spatial Proteomics and Multiplexed Staining Patents: Who Holds the Core Claims
Filing peaked in 2021 at 63 records, then eased to 53 by 2024 — a -16% shift over that span, not a collapsing field. Filings rose from zero in 2017 to a peak of 63 in 2021, then eased to 53 by 2024 — a -16% change over that three-year span. That is a normalization after a surge, not evidence of a shrinking field; 2025 and 2026 figures will keep revising upward as publication catches up with filing.
- 1AMBERGEN INC41
- 2SINGULAR GENOMICS SYSTEMS INC29
- 3MASSACHUSETTS INST OF TECH29
- 4THE BROAD INST INC27
- 5EVELO BIOSCIENCES INC27
See the full spatial proteomics and multiplexed staining analysis in Eureka
- The complete ranking, not just the top five
- Every IPC branch with its share of the corpus
- The most-cited records, and where claim space is still thin
Common questions about this landscape
How many patents exist for spatial proteomics and multiplexed staining?
This dataset covers 297 published records filed between 2015 and mid-2026, searched across terms like spatial proteomics, multiplexed immunofluorescence and imaging mass cytometry combined with antibody panel validation, signal spillover, cyclic staining and related concepts. That figure counts records, which is the level the assignee ranking uses. Because publication lags filing by roughly 18 months, the true count for 2025 and 2026 filings will keep rising as those applications publish.
Who are the leading patent holders in spatial proteomics?
The field is led by a single assignee with 41 records, well ahead of the rest of the ranking, with the top five assignees together holding 51.5% of all 297 records and the top ten holding 76.8%. The leaders are a mix of cancer research institutes, university technology offices and diagnostics companies rather than a single dominant commercial player. Beyond the top ten, filing spreads across a long tail of 73 ranked assignees total, many with only one or two records.
Is patent filing in this space growing or slowing down?
Filing rose steadily to a peak of 63 records in 2021, then eased to 53 by 2024, a -16% change over that three-year span. That reads as a normalization after a surge rather than a slowdown, and figures for 2025 and 2026 are still incomplete because of the typical 18-month gap between filing and publication. Judging momentum from the most recent one to two years alone would understate current activity.
Disclaimer. This analysis is based on Patsnap Eureka data drawn from a limited snapshot of global patent records and is provided for general information and reference only. Patent data carries inherent limitations — recent filings are under-counted because of publication lag, counts may be on a record or family basis, classification and applicant-name data may contain errors or duplicates, and the underlying search query defines the scope shown — so the analysis may be incomplete or inaccurate and may not reflect the full technology landscape.
Nothing here is an exhaustive prior-art, novelty, freedom-to-operate or validity search, nor does it constitute legal, financial or professional advice, and it should not be relied upon as such. Verify independently and review with qualified patent and legal professionals before acting on it.
Method: Filing trend and technology composition. Derived from a Patsnap search on Spatial Proteomics and Multiplexed Staining covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish. Every share divides by all records in scope. Data: Patsnap Eureka. See the full landscape report.