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Syngas Fermentation Media Patents: Who Leads, Trends 2026

Syngas Fermentation Media Patents: Who Leads, Trends 2026
https://www.patsnap.com/resources/blog/rd-blog/syngas-fermentation-media-optimization-patent-landscape/ · Patsnap · data cut-off 2026-07-31 · downloaded from the live page
Patent Landscape · Syngas Fermentation Media Optimization
Syngas Fermentation Media Optimization Patents: Concentration, Trends and Open Ground
  • 75.9% of the field sits with five filers. 258 of 340 records in scope belong to the top five assignees, with a long tail of single- and low-filing entrants behind them.
  • Filings have cooled from their 2019 peak. Output ran 36 in 2019 and the tracked three-year window shows a 45% decline from 2021 (11) to 2024 (6), the most recent complete year.
  • Bioreactor and gas-conversion classes trail the core fermentation class. C12M bioreactor apparatus reaches 37.9% of records and C25B electrolytic conversion only 8.2%, well behind C12P fermentation at 99.7%.
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340
Published Records
76%
Top-5 Share of All Records
-45%
Filing Growth 2021→2024
US
Leading Jurisdiction

Filing growth compares 2021 (11 records) with 2024 (6) — a three-year span. 2024 is the most recent year we treat as complete: publication lags filing by roughly 18 months, so 2025 onwards are still filling in and any growth rate that ends there would understate the field. Top-5 share is the combined record count of the five largest assignees divided by all 340 records in scope (CR5), not by the ranked leaders only.

Published byPatsnap Research··6 min readSourced from Patsnap Eureka
Overview

What this landscape covers

This landscape tracks 340 published records filed between 2015 and mid-2026 that combine syngas or acetogenic gas fermentation with medium-related claims: trace metal supply, vitamin dosing, redox control, nutrient limitation or sterilization. The scope is defined by IPC classes C12P7/40, C12P7/54 and C12M1/04, so it captures both the microbial conversion step and the bioreactor hardware around it, rather than gas-cleanup or syngas-generation patents filed elsewhere.

Because publication lags filing by roughly 18 months, the 2025 and 2026 counts in the trend data are still filling in and should not be read as a drop-off. The 2024 figure is the most recent year that can be treated as complete.

Filing activity and technology composition, 2015–2026
  1. 1LANZATECH INC79
  2. 2LANZATECH NEW ZEALAND LTD69
  3. 3LANZATECH NZ INC69
  4. 4SYNATA BIO INC24
  5. 5KIVERDI INC17
  6. 6JUPENG BIO HK LTD13
  7. 7INVISTA TEXTILES (U K) LTD8
  8. 8IOGEN CORPORATION8
  9. 9EMMAUS FOUND INC8
  10. 10BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY7
Source: Patsnap Eureka. Assignee ranking and totals. Derived from a Patsnap search on Syngas Fermentation Media Optimization covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
The data

Filing trend and technology composition

Two views of the same 340-record set: filings by year, and the IPC subclasses those filings carry. Because a single record can carry several IPC classes, the composition shares add up to more than 100% of records.

A 2019 peak followed by a cooling three-year window

Filings rose to a peak of 36 in 2019, then eased; the tracked window shows a 45% decline from 11 filings in 2021 to 6 in 2024, the most recent year with a complete count. Read 2025 and 2026 as still-arriving data rather than a continuing fall.

A 2019 peak followed by a cooling three-year window010203040222017201836201920202021202220232024202502026Most recent year is partial — publication lag means later filings are not yet visible.

Fermentation core dominates; conversion and separation are thin

C12P (fermentation and enzymatic synthesis) appears on 99.7% of records, effectively defining the set. C12N (microorganisms and genetic engineering) reaches 41.5% and C12M (bioreactor apparatus) 37.9%, while C25B (electrolytic conversion), C10L (fuels) and B01D (separation) each sit under 9% of records — signalling where claim density is far lower.

Fermentation core dominates; conversion and separation are thinC12P · Fermentation & enzymatic synth…33999.7%C12N · Microorganisms & genetic engin…14141.5%C12M · Bioreactors & enzyme apparatus12937.9%C12R · Microorganisms (index)4513.2%C01B · Non-metallic elements & inorga…298.5%C25B · Electrolytic production of com…288.2%C10L · Fuels & firelighters226.5%B01D · Separation processes (filtrati…175.0%Other8926.2%

Shares are the percentage of the 340 records in scope. A patent can carry several IPC classes, so the shares add up to more than 100%.

Source: Patsnap Eureka. Filing trend and technology composition. Derived from a Patsnap search on Syngas Fermentation Media Optimization covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.

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Key patents

The foundational grants and a recent filing

Representative recent filing
WO2024228166A12024-11-07

WO2024228166A1 — Acetogenic fermentation of carbon monoxide gas

CIRCE BIOTECHNOLOGIE GMBH

This invention relates to acetogenic gas fermentation, specifically of carbon monoxide (CO) gas and gas mixtures containing the same, typically comprised in synthesis gas or industrial waste gasses in fluctuating quantities, using acetogens (acetogenic bacteria), such as Thermoanaerobacter kivui (T. kivui). The invention finds particular application in industrial fermentation of the gaseous C1 substrates CO and CO2, as well as H2 and any mixture thereof, in bioreactors.Filed by Circe Biotechnologie, published November 2024 — outside the cluster of assignees that otherwise dominates this landscape.

WO2024228166A1 — patent drawing 1WO2024228166A1 — patent drawing 2
View full filing
Most-cited records in this landscape
#Publication no.Patent titleCitations
1US5593886AClostridium stain which produces acetic acid from waste gases743
2US6136577ABiological production of ethanol from waste gases with Clostridium ljungdahlii655
3WO1998000558A1Biological production of acetic acid from waste gases576
4US5807722ABiological production of acetic acid from waste gases with Clostridium ljungdahlii515
5US6340581B1Biological production of products from waste gases407
6WO2017165244A1Microorganisms and artificial ecosystems for the production of protein, food, and useful co-products from c1 …116
7US20200140901A1Process for using biogenic carbon dioxide derived from non-fossil organic material60
8US20130210096A1Methods and Systems for the Production of Hydrocarbon Products59
9WO2015058011A1Improved carbon capture in fermentation51
10US20120052541A1Improved carbon capture in fermentation31

Ranked by citation count within the searched corpus; older grants accumulate citations simply by being available longer, so treat this as a signal of influence on the field rather than of current filing activity.

Each row carries its publication number; clicking a row searches Eureka by that number.

Source: Patsnap Eureka. Citation counts and representative records. Derived from a Patsnap search on Syngas Fermentation Media Optimization covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
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Insights

What the numbers mean for a filing decision

Read alongside the concentration and composition figures, the dataset points to a field with a small, entrenched core and several thinly claimed branches around it.

Concentration
75.9%
of 340 records held by top 5 assignees

The core claim space is tightly held

The five leading assignees account for 258 of the 340 records in scope, with the leader alone credited with 79. New entrants filing directly against core fermentation-medium claims are filing into dense prior art held by a small group.

Top 5 combined, 258/340 records
Momentum
-45%
filings, 2021 to 2024

Filing pace has eased from its 2019 peak

Annual output peaked at 36 in 2019 and the tracked window shows an 11-to-6 decline between 2021 and 2024, the last complete year. That does not mean the underlying technology has matured — it means the easy claim space around the original strains and media formulations has largely been staked.

Peak 36 (2019); 2021=11 to 2024=6
Composition
8.2%
of records touch C25B electrolytic conversion

Hardware and hybrid-conversion claims are thin

C12M bioreactor apparatus reaches 37.9% of records, but adjacent classes covering electrolytic conversion (C25B, 8.2%), fuel derivatives (C10L, 6.5%) and separation (B01D, 5.0%) are all filed far less often than the fermentation core. These are narrower but comparatively open lanes.

C25B 28 records; C10L 22; B01D 17, of 340
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Eureka can read the same corpus for gaps instead of for coverage: under-claimed branches adjacent to syngas fermentation media optimization, with the prior art for and against each one.

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Source: Patsnap Eureka. Co-assignee relationships and derived observations. Derived from a Patsnap search on Syngas Fermentation Media Optimization covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
Players

Who is filing, and where the gate sits

The ranking covers 58 companies returned by the data endpoint across the full 340-record set — not a top-50 or top-100 cut. A handful of names hold most of the volume, and recent-year activity has gone quiet even among the leaders.

Leader
79 records
leading assignee

One filer sets the baseline for freedom-to-operate

The top-ranked assignee holds 79 of the 340 records, well ahead of fifth place at 17 and tenth place at 7. Any new medium-optimization claim needs to be checked against this filer's portfolio first.

Leader 79; 5th 17; 10th 7
Tail
88.8%
of records held by top 10

Concentration extends deep into the ranking

The top 10 assignees combine for 302 of 340 records, 88.8% of the field, leaving a genuinely long tail of low-count filers among the remaining 48 ranked companies.

Top 10 combined, 302/340 records
Momentum
0 in latest year
across several tracked assignees

Even the leaders show no filings in the latest tracked year

Several of the most active historical filers, including the leading group and named co-assignee pairs, show zero filings in the most recent year tracked. Given the 18-month publication lag, this reads as a reporting gap rather than confirmed withdrawal from the space.

Recent-year momentum: 0 across leading assignees
🔍
Under-claimed sub-areas worth a freedom-to-operate check
These sit outside the dense fermentation-medium core and carry comparatively few records.
Electrolytic co-conversion of syngasBioreactor redox-potential control hardwareTrace-metal dosing for mixed-culture systemsDownstream gas/liquid separation from fermentersSterilization protocols for continuous gas fermentation
Rank all filers by momentum →
Recent-year filing momentum by assignee
AssigneeRecent yearYoY
LanzaTech New Zealand Ltd0
LanzaTech Inc0-100%
LANZATECH NZ INC0
Kiverdi Inc0
Coskata Inc0
Jupeng Bio Inc0
Bioengineering Resources Inc0
INVISTA North America0
Source: Patsnap Eureka. Assignee-level momentum. Derived from a Patsnap search on Syngas Fermentation Media Optimization covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
What's next

Where to take this analysis

The published record only shows what has cleared examination or publication so far. Two follow-ups sharpen the picture before committing R&D or filing budget.

Map claims against the top five portfolios directly

With 75.9% of records held by five assignees, a claim-by-claim comparison against those portfolios is more informative than a broader landscape read.

Run a freedom-to-operate check in Eureka

Track the under-claimed branches as they fill in

Electrolytic conversion, redox-control hardware and separation claims are thin today but publication lag means recent activity has not fully surfaced yet.

Monitor white space in Eureka
Source: Patsnap Eureka. Forward-looking reading of the same dataset. Derived from a Patsnap search on Syngas Fermentation Media Optimization covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
FAQ

Common questions about this landscape

Answers are grounded in the same dataset. Derived from a Patsnap search on Syngas Fermentation Media Optimization covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP

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Disclaimer. This page is generated from Patsnap Eureka data drawn from a limited snapshot of global patent and scientific-literature records, and is provided for general information and reference only.

Patent data carries inherent limitations: recent filings (typically the most recent 18–24 months) are under-counted due to standard publication lag; counts may be reported at either a patent-family or a patent-record basis and are not always directly comparable; classification, applicant-name, and citation data may contain errors, duplicates, or omissions; and the underlying search query defines and constrains the scope shown. As a result, the analysis may be incomplete or inaccurate and may not reflect the full technology landscape.

Nothing on this page constitutes an exhaustive prior-art, novelty, freedom-to-operate, or validity search, nor does it constitute legal, financial, investment, or professional advice, and it should not be relied upon as such. Any patent, commercial, or strategic decision should be verified independently and reviewed with qualified patent, legal, and domain professionals. Patsnap makes no warranties, express or implied, as to the accuracy, completeness, or fitness for any particular purpose of the information presented.

Machine translation. Assignee and organisation names originally recorded in Chinese, Japanese or Korean have been rendered into English by an AI translation step so that the tables stay readable. These renderings are best-effort and may not match a company’s registered English name; the original name is what the underlying patent record carries, and it is what any Eureka query launched from this page uses.

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