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X-Ray Fluorescence Patents: Top Companies & Filing Trends 2026

X-Ray Fluorescence Patents: Top Companies & Filing Trends 2026
https://www.patsnap.com/resources/blog/rd-blog/x-ray-fluorescence-spectrometry-patent-landscape/ · Patsnap · data cut-off 2026-07-31 · downloaded from the live page
Patent Landscape · X-Ray Fluorescence Spectrometry
X-Ray Fluorescence Spectrometry Patents: Who Files, What They Claim
  • Filing has cooled from its 2019 peak of 653 records to 40 in the most recent (partial) year, with the 2021→2024 complete-year span down 37% from 494 to 310.
  • No single filer dominates: the leader holds 377 records and the top 5 combined reach only 11.8% of the 10,296 records in scope.
  • Material analysis (G01N) sits under medicinal preparations (A61K) in class frequency, signalling that a large share of this corpus is driven by pharmaceutical and polymer analytics rather than instrumentation alone.
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10.3K
Published Records
12%
Top-5 Share of All Records
-37%
Filing Growth 2021→2024
US
Leading Jurisdiction

Filing growth compares 2021 (494 records) with 2024 (310) — a three-year span. 2024 is the most recent year we treat as complete: publication lags filing by roughly 18 months, so 2025 onwards are still filling in and any growth rate that ends there would understate the field. Top-5 share is the combined record count of the five largest assignees divided by all 10,296 records in scope (CR5), not by the ranked leaders only.

Published byPatsnap Research··7 min readSourced from Patsnap Eureka
Overview

What the X-ray fluorescence patent record actually shows

X-ray fluorescence spectrometry patents in this dataset span 10,296 records filed between 2015 and mid-2026, covering matrix correction methods, fundamental-parameter calculations, detection-limit improvements, sample pelletizing, handheld analyzer design and calibration standards. The corpus is not a narrow instrumentation niche: it overlaps heavily with pharmaceutical composition claims (A61K, A61P) and polymer chemistry (C08F, C08L), which means a filing strategy built purely around detector hardware will miss where much of the competitive claim space actually sits.

Filing volume rose through the late 2010s, peaked in 2019, and has declined across the most recent complete years. Publication lags filing by roughly 18 months, so figures for 2025 and 2026 will fill in as later-filed applications publish; they should not yet be read as a slowdown.

Filing volume by year, 2017-2026
  1. 1DAIKIN INDUSTRIES LTD377
  2. 2BOREALIS AG256
  3. 3FUJIFILM CORP220
  4. 4BASF SE202
  5. 5CELGENE CORP155
  6. 6SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ BV153
  7. 7TEVA PHARMA IND LTD139
  8. 8ADEKA CORP133
  9. 9MITSUBISHI CHEM CORP109
  10. 10NOVARTIS AG108
Source: Patsnap Eureka. Assignee ranking and totals. Derived from a Patsnap search on X-Ray Fluorescence Spectrometry covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
The Data

Filing trend and technology composition

Two views of the same 10,296 records: how filing volume has moved year over year, and which IPC subclasses carry the claim density.

A cooling filing curve after a 2019 peak

Annual filings ran from 453 in 2017 to a peak of 653 in 2019, then eased across the following complete years, with the 2021-2024 span down 37% (494 to 310). The 2025-2026 figures are still incomplete because of publication lag and will rise as later filings post.

A cooling filing curve after a 2019 peak0200400600800453201720186532019202020212022202320242025402026Most recent year is partial — publication lag means later filings are not yet visible.

Composition skews toward chemical and pharmaceutical use classes

A61K (medicinal preparations) leads at 19.9% of the 10,296 records, ahead of G01N (material analysis and testing) at 14.6% and C07D (heterocyclic compounds) at 13.2%. Because records can carry multiple IPC classes, these shares sum to more than 100% and should be read as overlap, not as a partition of the field.

Composition skews toward chemical and pharmaceutical use classesA61K · Medicinal preparations2,05219.9%G01N · Material analysis & testing1,49914.6%C07D · Heterocyclic compounds1,35813.2%A61P · Therapeutic activity of compou…1,13311.0%B01J · Chemical/physical processes & …1,03410.0%C08F · Addition polymers (vinyl etc.)9168.9%C08L · Polymer compositions7617.4%C07C · Acyclic & carbocyclic compounds7116.9%Other12,013116.7%

Shares are the percentage of the 10,296 records in scope. A patent can carry several IPC classes, so the shares add up to more than 100%.

Source: Patsnap Eureka. Filing trend and technology composition. Derived from a Patsnap search on X-Ray Fluorescence Spectrometry covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.

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Key Patents

A representative claim in calibration methodology

Representative Record
US6519543B12003-02-11

US6519543B1 — Calibration method for quantitative elemental analysis

BELL SEMICONDUCTOR, LLC

The method determines a concentration of an element within a known matrix, obtains a calibration standard of that matrix via a polishing process representative of the concentration, and derives a detection limit of the analytical tool with respect to that concentration. Secondary ion mass spectrometry may be used to establish the element concentration within the known matrix.Filed by Bell Semiconductor, LLC; granted 2003-02-11.

US6519543B1 — patent drawing 1US6519543B1 — patent drawing 2
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Most-cited records in the X-ray fluorescence corpus
#Publication no.Patent titleCitations
1US6454811B1Composites for tissue regeneration and methods of manufacture thereof523
2US6601776B1Liquid atomization methods and devices480
3WO1999064638A1Removal of oxygen from metal oxides and solid solutions by electrolysis in a fused salt432
4US5591581AElectrochemiluminescent rhenium moieties and methods for their use406
5US20150364747A1Materials for solid state electrolytes and protective electrode coatings for lithium batteries400
6US6719828B1High capacity regenerable sorbent for removal of mercury from flue gas391
7US20070131915A1Stable dispersions of polymer-coated graphitic nanoplatelets378
8EP0874005A1Olefin polymerization catalysts, transition metal compounds, processes for olefin polymerization, and Alpha-o…375
9WO2010052263A1Solid catalyst composition285
10US20160116839A1Organometallic solution based high resolution patterning compositions and corresponding methods282

Citation counts favour older records simply because they have had longer to accumulate citations inside the searched corpus; treat them as a signal of influence, not of current commercial relevance.

Each row carries its publication number; clicking a row searches Eureka by that number.

Source: Patsnap Eureka. Citation counts and representative records. Derived from a Patsnap search on X-Ray Fluorescence Spectrometry covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
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Insights

What the concentration and citation figures mean for a filing decision

Three figures matter more than the raw record count: how concentrated ownership is at the top, how the technology composition splits across use cases, and how citation weight is distributed.

Concentration
11.8%
of 10,296 records held by top 5 assignees

Ownership is dispersed, not cornered

The leading assignee holds 377 records and fifth place holds 155, yet the top five combined reach only 11.8% of all records in scope. Extending to the top ten adds only another 6.2 percentage points to reach 18.0%. That leaves the large majority of filings spread across a long tail of single- and few-filing entrants.

Based on the 100-company ranking returned by the dataset.
Technology mix
19.9%
of records classed under A61K

Pharmaceutical use drives much of the corpus

Medicinal preparations (A61K) and therapeutic activity (A61P) together account for a substantial share of records, ahead of material analysis and testing (G01N) itself. Filers focused purely on instrumentation should expect to compete for claim space with pharmaceutical and polymer analytics filers using XRF as an analytical tool within a broader composition claim.

Shares are of the same 10,296-record denominator and overlap because records carry multiple IPC classes.
Filing momentum
-37%
change 2021 to 2024

A cooling curve, not a dead field

Complete-year filings fell from 494 in 2021 to 310 in 2024. Because publication lags filing by roughly 18 months, the 2025 and 2026 figures are still incomplete and should not be read into this trend; the 2021-2024 window is the most reliable recent signal.

Peak filing year to date is 2019, at 653 records.
Eureka AI Agent
Looking for what nobody has claimed yet?

Eureka can read the same corpus for gaps instead of for coverage: under-claimed branches adjacent to x-ray fluorescence spectrometry, with the prior art for and against each one.

Find the white space →
Source: Patsnap Eureka. Co-assignee relationships and derived observations. Derived from a Patsnap search on X-Ray Fluorescence Spectrometry covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
Players

A fragmented field with a handful of repeat filers

No single company controls the field. The leader's 377 records represent a real position, but the bulk of activity is spread across a long tail, and several previously active filers have gone quiet in the most recent year.

Leader position
377
records held by the top-ranked assignee

A clear leader without a dominant share

The top-ranked assignee's 377 records outpace the field, but that still represents a small fraction of the 10,296 records in scope, leaving substantial room for new entrants to build a competing position.

Fifth place holds 155 records; tenth place holds 108.
Momentum
-67% to -100%
YoY change among several top filers

Recent-year activity has slowed sharply among incumbents

Several of the most active historical filers show steep year-over-year declines in their latest reported year, with some down to zero filings. This is consistent with the broader 2021-2024 decline rather than an isolated retreat by any one firm.

Momentum figures reflect the latest reported year per assignee.
Collaboration
10
co-assignee pairs identified

Co-filing is rare and concentrated in a few relationships

Only ten co-assignee pairs appear in the dataset, and the strongest of these involves a small cluster of related corporate entities rather than cross-industry partnerships. Most patent activity in this field is filed by a single assignee acting alone.

Strongest pair recorded 18 shared filings.
🔍
Under-claimed branches worth checking before filing
Areas where filing density is comparatively thin relative to the core matrix-correction and calibration-standard claims.
Portable/handheld detector miniaturisationFundamental-parameter algorithm refinementsSample pelletizing for heterogeneous matricesLow-detection-limit trace element methodsField calibration standard formats
Rank all filers by momentum →
Assignee momentum, most recent reported year
AssigneeRecent yearYoY
Daikin Industries, Ltd.10-67%
Fujifilm Corporation1-91%
Mitsubishi Chemical Corporation1-75%
Borealis AG0-100%
BASF SE0-100%
Shell Internationale Research Maatschappij B.V.0
Celgene Corporation0-100%
Teva Pharmaceutical Industries Ltd.0
Source: Patsnap Eureka. Assignee-level momentum. Derived from a Patsnap search on X-Ray Fluorescence Spectrometry covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
What's Next

Where to take this analysis

The dataset points to a fragmented ownership structure and several specific sub-areas with thinner filing density. Turning that into a filing or freedom-to-operate decision requires drilling into the actual claim language.

Map claim scope on the calibration-method cluster

Representative records like US6519543B1 show how calibration and detection-limit claims are constructed; checking claim breadth against a new method before filing avoids costly overlap.

Explore claim charts in Eureka

Track momentum shifts among incumbent filers

Several previously active assignees have slowed sharply in the most recent reported year, which may open filing space that would have been contested two years ago.

Monitor assignee activity in Eureka

Test white-space branches against prior art

Under-claimed areas such as handheld analyzer miniaturisation or field calibration formats look thin in this dataset, but a proper prior-art search is needed before committing R&D spend.

Run a white space search in Eureka
Source: Patsnap Eureka. Forward-looking reading of the same dataset. Derived from a Patsnap search on X-Ray Fluorescence Spectrometry covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP
FAQ

Common questions about X-ray fluorescence spectrometry patents

Answers are grounded in the same dataset. Derived from a Patsnap search on X-Ray Fluorescence Spectrometry covering 2015–2026, data cut-off 2026-07-31. Counts reflect published records only and shift as new filings publish.Run this in Eureka MCP

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Disclaimer. This page is generated from Patsnap Eureka data drawn from a limited snapshot of global patent and scientific-literature records, and is provided for general information and reference only.

Patent data carries inherent limitations: recent filings (typically the most recent 18–24 months) are under-counted due to standard publication lag; counts may be reported at either a patent-family or a patent-record basis and are not always directly comparable; classification, applicant-name, and citation data may contain errors, duplicates, or omissions; and the underlying search query defines and constrains the scope shown. As a result, the analysis may be incomplete or inaccurate and may not reflect the full technology landscape.

Nothing on this page constitutes an exhaustive prior-art, novelty, freedom-to-operate, or validity search, nor does it constitute legal, financial, investment, or professional advice, and it should not be relied upon as such. Any patent, commercial, or strategic decision should be verified independently and reviewed with qualified patent, legal, and domain professionals. Patsnap makes no warranties, express or implied, as to the accuracy, completeness, or fitness for any particular purpose of the information presented.

Machine translation. Assignee and organisation names originally recorded in Chinese, Japanese or Korean have been rendered into English by an AI translation step so that the tables stay readable. These renderings are best-effort and may not match a company’s registered English name; the original name is what the underlying patent record carries, and it is what any Eureka query launched from this page uses.

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